2024

Aude Jary, Yongsoo Kim, Kirsten Rozemeijer, Paul P. Eijk, Ramon P. van der Zee, Maaike C.G. Bleeker, Saskia M. Wilting, Renske D.M. Steenbergen

Accurate detection of copy number aberrations in FFPE samples using the mFAST-SeqS approach

Exp Mol Pathol. 2024 Jun:137:104906. doi: 10.1016/j.yexmp.2024.104906. Epub 2024 May 30. PMID:38820761

Huseinovic A, Xu M, Jaspers A, Bais B, Steenbergen RDM.

miR-129-5p inhibits anchorage-independent growth through silencing of ACTN1 and the ELK4/c-FOS axis in HPV-transformed keratinocytes.
J Med Virol. 2024 Apr;96(4):e29580. doi: 10.1002/jmv.29580.

PMID: 38566572

Voss FO, van Beurden M, Veelders KJ, Bruggink AH, Steenbergen RDM, Berkhof J, Bleeker MCG.

Incidence and Risk Factors for Recurrence and Progression of HPV-Independent Vulvar Intraepithelial Neoplasia.
J Low Genit Tract Dis. 2024 Apr 1;28(2):153-159. doi: 10.1097/LGT.0000000000000794. Epub 2024 Jan 10.

PMID: 38518213

Wever BMM, Steenbergen RDM.

Unlocking the potential of tumor-derived DNA in urine for cancer detection: methodological challenges and opportunities.
Mol Oncol. 2024 Mar 10. doi: 10.1002/1878-0261.13628. Online ahead of print.

PMID: 38462745

Thuijs NB, van Beurden M, Duin S, Heideman DAM, Berkhof J, Steenbergen RDM, Bleeker MCG.

High-grade vulvar intraepithelial neoplasia: comprehensive characterization and long-term vulvar carcinoma risk.
Histopathology. 2024 Jan;84(2):301-314. doi: 10.1111/his.15050. Epub 2023 Sep 19.

PMID: 37726173

2023

Rozemeijer K, Dias Gonçalves Lima F, Ter Braak TJ, Hesselink AT, Prins JM, de Vries HJC, Steenbergen RDM.

Analytical validation and diagnostic performance of the ASCL1/ZNF582 methylation test for detection of high-grade anal intraepithelial neoplasia and anal cancer.
Tumour Virus Res. 2023 Dec 30;17:200275. doi: 10.1016/j.tvr.2023.200275. Online ahead of print.

PMID: 38160718

Wever BMM, van den Helder R, van Splunter AP, van Gent MDJM, Kasius JC, Trum JW, Verhoeve HR, van Baal WM, Hulbert A, Verhoef L, Heideman DAM, Lissenberg-Witte BI, van Trommel NE, Steenbergen RDM, Bleeker MCG.

DNA methylation testing for endometrial cancer detection in urine, cervicovaginal self-samples and cervical scrapes.

Int J Cancer. 2023 Mar 13. doi: 10.1002/ijc.34504.

PMID: 36912267

Dick S, Heideman DAM, Mom CH, Meijer CJLM, Berkhof J, Steenbergen RDM, Bleeker MCG.

Methylation testing for the detection of recurrent cervical intraepithelial neoplasia.

Int J Cancer. 2023 Dec 15;153(12):2011-2018. doi: 10.1002/ijc.34678. Epub 2023 Aug 4.

PMID: 37539971

Voss FO, Thuijs NB, Duin S, Özer M, van Beurden M, Berkhof J, Steenbergen RDM, Bleeker MCG.

Clinical validation of methylation biomarkers for optimal detection of high-grade vulvar intraepithelial neoplasia.

Int J Cancer. 2023 Apr 19. doi: 10.1002/ijc.34537.

PMID:37074263

Thuijs NB, van Beurden M, Duin S, Heideman DAM, Berkhof J, Steenbergen RDM, Bleeker MCG.

High-grade vulvar intraepithelial neoplasia: comprehensive characterization and long-term vulvar carcinoma risk.

Histopathology. 2023 Sep 19. doi: 10.1111/his.15050. Online ahead of print.

PMID: 37726173

Verhoef L, Bleeker MCG, Polman N, Steenbergen RDM, Ebisch RMF, Melchers WJG, Bekkers RLM, Molijn AC, Quint WG, van Kemenade F, Meijer CJLM, Berkhof J, Heideman DAM.

Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening.

Br J Cancer. 2023 Jul;129(1):104-111. doi: 10.1038/s41416-023-02277-z. Epub 2023 Apr 26.

PMID: 37100874

Vink FJ, Meijer CJLM, Hesselink AT, Floore AN, Lissenberg-Witte BI, Bonde JH, Pedersen H, Cuschieri K, Bhatia R, Poljak M, Oštrbenk Valenčak A, Hillemanns P, Quint WGV, Del Pino M, Kenter GG, Steenbergen RDM, Heideman DAM, Bleeker MCG.

FAM19A4/miR124-2 Methylation Testing and Human Papillomavirus (HPV) 16/18 Genotyping in HPV-Positive Women Under the Age of 30 Years.

Clin Infect Dis. 2023 Feb 8;76(3):e827-e834. doi: 10.1093/cid/ciac433.

PMID: 35686306

Vink FJ, Meijer CJLM, Lissenberg-Witte BI, Visser C, Duin S, Snyman LC, Richter KL, van der Merwe FH, Botha MH, Steenbergen RDM, Dreyer G.

Validation of ASCL1 and LHX8 Methylation Analysis as Primary Cervical Cancer Screening Strategy in South African Women with Human Immunodeficiency Virus.

Clin Infect Dis. 2023 Feb 8;76(3):416-423. doi: 10.1093/cid/ciac801.

PMID: 36366827

Xu M, Huseinovic A, Jaspers A, Yuan L, Steenbergen RDM.J

Downregulation of miR-193a/b-3p during HPV-induced cervical carcinogenesis contributes to anchorage-independent growth through PI3K-AKT pathway regulators.
J Med Virol. 2023 Mar;95(3):e28589. doi: 10.1002/jmv.28589.

PMID: 36799263

2022

Bach S, Wever BMM, van de Wiel MA, Veltman JD, Hashemi SMS, Kazemier G, Bahce I, Steenbergen RDM.

Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients.

Epigenetics. 2022 Oct;17(10):1057-1069. doi: 10.1080/15592294.2021.1982511. Epub 2021 Oct 4.

PMID: 34605346

Dias Gonçalves Lima F, van der Zee RP, Dick S, van Noesel CJM, Berkhof J, Schim van der Loeff MF, Prins JM, Steenbergen RDM, de Vries HJC.
DNA Methylation Analysis to predict Regression of high-grade anal Intraepithelial Neoplasia in HIV+ men (MARINE): a cohort study protocol.
BMJ Open. 2022 Aug 3;12(8):e060301. doi: 10.1136/bmjopen-2021-060301.
PMID: 35922105

van den Helder R, Steenbergen RDM, van Splunter AP, Mom CH, Tjiong MY, Martin I, Rosier-van Dunné FMF, van der Avoort IAM, Bleeker MCG, van Trommel NE.
HPV and DNA Methylation Testing in Urine for Cervical Intraepithelial Neoplasia and Cervical Cancer Detection.
Clin Cancer Res. 2022 May 13;28(10):2061-2068. doi: 10.1158/1078-0432.CCR-21-3710.
PMID: 35266975

Hentschel AE, Beijert IJ, Bosschieter J, Kauer PC, Vis AN, Lissenberg-Witte BI, van Moorselaar RJA, Steenbergen RDM, Nieuwenhuijzen JA.
Bladder cancer detection in urine using DNA methylation markers: a technical and prospective preclinical validation.
Clin Epigenetics. 2022 Feb 5;14(1):19. doi: 10.1186/s13148-022-01240-8.
PMID: 35123558

Huseinovic A, Jaspers A, van Splunter AP, Sørgård H, Wilting SM, Swarts DRA, van der Meulen IH, van Beusechem VW, de Menezes RX, Steenbergen RDM.
Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.
Int J Mol Sci. 2022 Apr 26;23(9):4791. doi: 10.3390/ijms23094791.
PMID: 35563182

Kremer WW, Dick S, Heideman DAM, Steenbergen RDM, Bleeker MCG, Verhoeve HR, van Baal WM, van Trommel N, Kenter GG, Meijer CJLM, Berkhof J.
Clinical Regression of High-Grade Cervical Intraepithelial Neoplasia Is Associated With Absence of FAM19A4/miR124-2 DNA Methylation (CONCERVE Study).
J Clin Oncol. 2022 May 5:JCO2102433. doi: 10.1200/JCO.21.02433. Online ahead of print.
PMID: 35512257

Schaafsma M, van den Helder R, Bleeker MCG, Rosier-van Dunné F, van der Avoort IAM, Steenbergen RDM, van Trommel NE.
Experiences and preferences towards collecting a urine and cervicovaginal self-sample among women attending a colposcopy clinic.
Prev Med Rep. 2022 Feb 28;26:101749. doi: 10.1016/j.pmedr.2022.101749. eCollection 2022 Apr.
PMID: 35256928

Verhoef L, Bleeker MCG, Polman N, Steenbergen RDM, Meijer CJLM, Melchers WJG, Bekkers RL, Molijn AC, Quint WG, van Kemenade FJ, Berkhof J, Heideman DAM.
Performance of DNA methylation analysis of ASCL1, LHX8, ST6GALNAC5, GHSR, ZIC1 and SST for the triage of HPV-positive women: Results from a Dutch primary HPV-based screening cohort.
Int J Cancer. 2022 Feb 1;150(3):440-449. doi: 10.1002/ijc.33820. Epub 2021 Oct 13.
PMID: 34558659

Verhoef L, Floore AN, Doorn S, Cuschieri K, Bhatia R, Hesselink AT, Meijer CJLM, Steenbergen RDM, Heideman DAM.

Direct bisulphite conversion of cervical samples for DNA methylation analysis.

Epigenetics. 2022 Oct;17(10):1173-1179. doi: 10.1080/15592294.2021.1992911. Epub 2021 Oct 27.

PMID: 34652264

Vink FJ, Meijer CJLM, Hesselink AT, Floore AN, Lissenberg-Witte BI, Bonde JH, Pedersen H, Cuschieri K, Bhatia R, Poljak M, Oštrbenk Valenčak A, Hillemanns P, Quint WGV, Del Pino M, Kenter GG, Steenbergen RDM, Heideman DAM, Bleeker MCG.
FAM19A4/miR124-2 methylation testing and HPV16/18 genotyping in HPV-positive women under the age of 30 years.
Clin Infect Dis. 2022 Jun 10:ciac433. doi: 10.1093/cid/ciac433. Online ahead of print.
PMID: 35686306

Vink FJ, Steenbergen RDM, Kremer WW, Lissenberg-Witte BI, Heideman DAM, Bleeker MCG, van Zummeren M, Breytenbach E, Visser C, Lukhwareni A, Meijer CJLM, Dreyer G.
Posttreatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3.
AIDS. 2022 Jun 1;36(7):953-961. doi: 10.1097/QAD.0000000000003197. Epub 2022 Feb 15.
PMID: 35152224

Wever BMM, Bach S, Tibbesma M, Ter Braak TJ, Wajon D, Dickhoff C, Lissenberg-Witte BI, Hulbert A, Kazemier G, Bahce I, Steenbergen RDM.
Detection of non-metastatic non-small-cell lung cancer in urine by methylation-specific PCR analysis: A feasibility study.
Lung Cancer. 2022 Aug;170:156-164. doi: 10.1016/j.lungcan.2022.06.013. Epub 2022 Jun 22.
PMID: 35793574

 

2021

Bach S, Wever BMM, van de Wiel MA, Veltman JD, Hashemi SMS, Kazemier G, Bahce I, Steenbergen RDM.
Dynamics of methylated cell-free DNA in the urine of non-small cell lung cancer patients.
Epigenetics. 2021 Oct 4:1-13. doi: 10.1080/15592294.2021.1982511. Online ahead of print.
PMID: 34605346

Bach S, Paulis I, Sluiter NR, Tibbesma M, Martin I, van de Wiel MA, Tuynman JB, Bahce I, Kazemier G, Steenbergen RDM.
Detection of colorectal cancer in urine using DNA methylation analysis.
Sci Rep. 2021 Jan 27;11(1):2363. doi: 10.1038/s41598-021-81900-6.

Hentschel AE, van den Helder R, van Trommel NE, van Splunter AP, van Boerdonk RAA, van Gent MDJM, Nieuwenhuijzen JA, Steenbergen RDM.
The Origin of Tumor DNA in Urine of Urogenital Cancer Patients: Local Shedding and Transrenal Excretion.
Cancers (Basel). 2021 Jan 31;13(3):535. doi: 10.3390/cancers13030535.
PMID: 33572525

Hentschel AE, van der Toom EE, Vis AN, Ket JCF, Bosschieter J, Heymans MW, van Moorselaar RJA, Steenbergen RDM, Nieuwenhuijzen JA.
A systematic review on mutation markers for bladder cancer diagnosis in urine.
BJU Int. 2021 Jan;127(1):12-27. doi: 10.1111/bju.15137. Epub 2020 Aug 16.
PMID: 32539176

Hentschel, A.E.; van den Helder, R.; van Trommel, N.E.; van Splunter, A.P.; van Boerdonk, R.A.A.; van Gent, M.D.J.M.; Nieuwenhuijzen, J.A.; Steenbergen, R.D.M.
The Origin of Tumor DNA in Urine of Urogenital Cancer Patients: Local Shedding and Transrenal Excretion.
Cancers 2021, 13, 535. https://doi.org/10.3390/ cancers13030535

Kremer WW, Steenbergen R, Heideman D, Kenter GG, Meijer C.
The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review.
BJOG. 2021 Feb;128(3):504-514. doi: 10.1111/1471-0528.16395. Epub 2020 Aug 9.
PMID: 32619334

Téblick L, Van Keer S, De Smet A, Van Damme P, Laeremans M, Rios Cortes A, Beyers K, Vankerckhoven V, Matheeussen V, Mandersloot R, Floore A, Meijer CJLM, Steenbergen RDM, Vorsters A.
Impact of Collection Volume and DNA Extraction Method on the Detection of Biomarkers and HPV DNA in First-Void Urine.
Molecules. 2021 Apr 1;26(7):1989. doi: 10.3390/molecules26071989.
PMID: 33915837

Thuijs NB, Schonck WAM, Klaver LLJ, Fons G, van Beurden M, Steenbergen RDM, Bleeker MCG.
Biomarker Expression in Multifocal Vulvar High-Grade Squamous Intraepithelial Lesions.
Cancers (Basel). 2021 Nov 11;13(22):5646. doi: 10.3390/cancers13225646.
PMID: 34830799

Thuijs NB, Schonck WAM, Klaver LLJ, Fons G, van Beurden M, Steenbergen RDM, Bleeker MCG.
Biomarker Expression in Multifocal Vulvar High-Grade Squamous Intraepithelial Lesions.
Cancers (Basel). 2021 Nov 11;13(22):5646. doi: 10.3390/cancers13225646.
PMID: 34830799

Thuijs NB, Berkhof J, Özer M, Duin S, van Splunter AP, Snoek BC, Heideman DAM, van Beurden M, Steenbergen RDM, Bleeker MCG.
DNA methylation markers for cancer risk prediction of vulvar intraepithelial neoplasia.
Int J Cancer. 2021 Jan 10;148(10):2481-8. doi: 10.1002/ijc.33459. Online ahead of print.
PMID: 33426639

Thuijs NB, van Beurden M, Bruggink AH, Steenbergen RDM, Berkhof J, Bleeker MCG.
Vulvar intraepithelial neoplasia: Incidence and long-term risk of vulvar squamous cell carcinoma.
Int J Cancer. 2021 Jan 1;148(1):90-98. doi: 10.1002/ijc.33198. Epub 2020 Jul 22.
PMID: 32638382

Van Keer S, van Splunter AP, Pattyn J, De Smet A, Herzog SA, Van Ostade X, Tjalma WAA, Ieven M, Van Damme P, Steenbergen RDM, Vorsters A.
Triage of human papillomavirus infected women by methylation analysis in first-void urine.
Sci Rep. 2021 Apr 12;11(1):7862. doi: 10.1038/s41598-021-87329-1.
PMID: 33846517

Verhoef L, Floore AN, Doorn S, Cuschieri K, Bhatia R, Hesselink AT, Meijer CJLM, Steenbergen RDM, Heideman DAM.
Direct bisulphite conversion of cervical samples for DNA methylation analysis.
Epigenetics. 2021 Oct 27:1-7. doi: 10.1080/15592294.2021.1992911. Online ahead of print.
PMID: 34652264

Vink FJ, Lissenberg-Witte BI, Meijer CJLM, Berkhof J, van Kemenade FJ, Siebers AG, Steenbergen RDM, Bleeker MCG, Heideman DAM.
FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort.
Clin Microbiol Infect. 2021 Jan;27(1):125.e1-125.e6. doi: 10.1016/j.cmi.2020.03.018. Epub 2020 Mar 25.
PMID: 32222459

Frederique J Vink, Stèfanie Dick, Daniëlle A M Heideman, Lise M A De Strooper, Renske D M Steenbergen, Birgit I Lissenberg-Witte, DNTP Group; Arno Floore, Jesper H Bonde, Anja Oštrbenk Valenčak, Mario Poljak, Karl U Petry, Peter Hillemanns, Nienke E van Trommel, Johannes Berkhof, Maaike C G Bleeker, Chris J L M Meijer
Classification of high-grade cervical intraepithelial neoplasia by p16 ink4a , Ki-67, HPV E4 and FAM19A4/miR124-2 methylation status demonstrates considerable heterogeneity with potential consequences for management
Int J Cancer. 2021 Aug 1;149(3):707-716. doi: 10.1002/ijc.33566. Epub 2021 May 11

van der Zee RP, Meijer CJLM, Cuming T, Kreuter A, van de Sandt MM, Quint WGV, de Vries HJC, Prins JM, Steenbergen RDM.
Characterisation of anal intraepithelial neoplasia and anal cancer in HIV-positive men by immunohistochemical markers p16, Ki-67, HPV-E4 and DNA methylation markers.
Int J Cancer. 2021 Nov 15;149(10):1833-1844. doi: 10.1002/ijc.33748. Epub 2021 Aug 4.
PMID: 34310698

van der Zee RP, van Noesel CJM, Martin I, Ter Braak TJ, Heideman DAM, de Vries HJC, Prins JM, Steenbergen RDM.
DNA methylation markers have universal prognostic value for anal cancer risk in HIV-negative and HIV-positive individuals.
Mol Oncol. 2021 Nov;15(11):3024-3036. doi: 10.1002/1878-0261.12926. Epub 2021 Mar 16.
PMID: 33580586

van der Zee RP, Richel O, van Noesel CJM, Ciocănea-Teodorescu I, van Splunter AP, Ter Braak TJ, Nathan M, Cuming T, Sheaff M, Kreuter A, Meijer CJLM, Quint WGV, de Vries HJC, Prins JM, Steenbergen RDM.
Cancer Risk Stratification of Anal Intraepithelial Neoplasia in Human Immunodeficiency Virus-Positive Men by Validated Methylation Markers Associated With Progression to Cancer.
Clin Infect Dis. 2021 Jun 15;72(12):2154-2163. doi: 10.1093/cid/ciaa397.
PMID: 32266940

Ramon P van der Zee, Carel J M van Noesel, Ivonne Martin, Timo J Ter Braak, Daniëlle A M Heideman, Henry J C de Vries , Jan M Prins, Renske D M Steenbergen
DNA methylation markers have universal prognostic value for anal cancer risk in HIV-negative and HIV-positive individuals
Mol Oncol. 2021 Feb 12. doi: 10.1002/1878-0261.12926. Online ahead of print.

2020

Babion I, Miok V, Jaspers A, Huseinovic A, Steenbergen RDM, van Wieringen WN, Wilting SM.
Identification of Deregulated Pathways, Key Regulators, and Novel miRNA-mRNA Interactions in HPV-Mediated Transformation.
Cancers (Basel). 2020 Mar 16;12(3). pii: E700. doi: 10.3390/cancers12030700.

Dick S, Verhoef L, De Strooper LM, Ciocănea-Teodorescu I, Wisman GBA, Meijer CJ, Bleeker MC, Steenbergen RD, Heideman DA.
Evaluation of six methylation markers derived from genome-wide screens for detection of cervical precancer and cancer
Epigenomics. 2020 Sep;12(18):1569-1578. doi: 10.2217/epi-2019-0331. Epub 2020 Sep 17

van den Helder R, Wever BMM, van Trommel NE, van Splunter AP, Mom CH, Kasius JC, Bleeker MCG,
Non-invasive detection of endometrial cancer by DNA methylation analysis in urine.
Clin Epigenetics. 2020 Nov 3;12(1):165. doi: 10.1186/s13148-020-00958-7.

den Helder RV, Wever BM, van Trommel JA, Ket JC, Bleeker MC, Steenbergen RD, van Trommel NE.
DNA methylation markers for endometrial cancer detection in minimally invasive samples: a systematic review.
Epigenomics. 2020 Sep;12(18):1661-1672. doi: 10.2217/epi-2020-0164. Epub 2020 Sep 17.

van den Helder R, van Trommel NE, van Splunter AP, Lissenberg-Witte BI, Bleeker MCG, Steenbergen RDM.
Methylation analysis in urine fractions for optimal CIN3 and cervical cancer detection.
Papillomavirus Res. 2020 Mar 13;9:100193. doi: 10.1016/j.pvr.2020.100193. [Epub ahead of print]

Hentschel AE, van der Toom EE, Vis AN, Ket JCF, Bosschieter J, Heymans MW, van Moorselaar RJA, Steenbergen RDM, Nieuwenhuijzen JA.
A systematic review on mutation markers for bladder cancer diagnosis in urine.
BJU Int. 2020 Jun 15. doi: 10.1111/bju.15137. Online ahead of print.

Hentschel AE, Nieuwenhuijzen JA, Bosschieter J, Splunter APV, Lissenberg-Witte BI, Voorn JPV, Segerink LI, Moorselaar RJAV, Steenbergen RDM.
Comparative Analysis of Urine Fractions for Optimal Bladder Cancer Detection Using DNA Methylation Markers.
Cancers (Basel). 2020 Apr 2;12(4):859. doi: 10.3390/cancers12040859.

Kremer WW, Steenbergen R, Heideman D, Kenter GG, Meijer C.
The use of host cell DNA methylation analysis in the detection and management of women with advanced cervical intraepithelial neoplasia: a review.
BJOG. 2020 Jul 3. doi: 10.1111/1471-0528.16395. Online ahead of print.

Kremer WW, Vink FJ, van Zummeren M, Dreyer G, Rozendaal L, Doorbar J, Bleeker MCG, Meijer CJLM.
Characterization of cervical biopsies of women with HIV and HPV co-infection using p16ink4a, ki-67 and HPV E4 immunohistochemistry and DNA methylation.
Mod Pathol. 2020 Apr 6. doi: 10.1038/s41379-020-0528-x. [Epub ahead of print]

Leeman A, Jenkins D, Marra E, van Zummeren M, Pirog EC, van de Sandt MM, van Eeden A, Schim van der Loeff MF, Doorbar J, de Vries HJC, van Kemenade FJ, Meijer CJLM, Quint WGV.
Grading immunohistochemical markers p16INK4a and HPV E4 identifies productive and transforming lesions caused by low- and high-risk HPV within high-grade anal squamous intraepithelial lesions.
Br J Dermatol. 2020 Apr;182(4):1026-1033. doi: 10.1111/bjd.18342. Epub 2019 Oct 2.

Leeman A, Jenkins D, Del Pino M, Ordi J, Torné A, Doorbar J, Meijer CJLM, van Kemenade FJ, Quint WGV.
Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124-2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions.
Cancer Med. 2020 Apr;9(7):2454-2461. doi: 10.1002/cam4.2855. Epub 2020 Feb 5.

Mes SW, Heideman DAM, Bloemena E, Brink A, Bogaarts M, Leemans CR, Brakenhoff RH.
Development and Validation of a Novel and Rapid Molecular Detection Method for High-Risk Human Papillomavirus in Formalin-Fixed, Paraffin-Embedded Tumor Tissue.
J Mol Diagn. 2020 Feb;22(2):262-271. doi: 10.1016/j.jmoldx.2019.10.009. Epub 2019 Dec 16.

Mpunga T, Chantal Umulisa M, Tenet V, Rugwizangoga B, Milner DA Jr, Munyanshongore C, Heideman DAM, Bleeker MCG, Tommasino M, Franceschi S, Baussano I, Gheit T, Sayinzoga F, Clifford GM.
Human papillomavirus genotypes in cervical and other HPV-related anogenital cancer in Rwanda, according to HIV status.
Int J Cancer. 2020 Mar 15;146(6):1514-1522. doi: 10.1002/ijc.32491. Epub 2019 Jun 26.

Rianne van den Helder1,2, Birgit M. M. Wever1, Nienke E. van Trommel2, Annina P. van Splunter1,
Constantijne H. Mom3, Jenneke C. Kasius3, Maaike C. G. Bleeker1 and Renske D. M. Steenbergen1
Non‑invasive detection of endometrial cancer by DNA methylation analysis in urine
Clin Epigenet (2020) 12:165 https://doi.org/10.1186/s13148-020-00958-7

Thuijs NB, Berkhof J, Özer M, Duin S, van Splunter AP, Snoek BC, Heideman DAM, van Beurden M, Steenbergen RDM, Bleeker MCG.
DNA methylation markers for cancer risk prediction of vulvar intraepithelial neoplasia.
Int J Cancer. 2021 Jan 10. doi: 10.1002/ijc.33459. Online ahead of print.

Thuijs NB, van Beurden M, Bruggink AH, Steenbergen RDM, Berkhof J, Bleeker MCG.
Vulvar intraepithelial neoplasia: Incidence and long-term risk of vulvar squamous cell carcinoma.
Int J Cancer. 2020 Jul 7. doi: 10.1002/ijc.33198. Online ahead of print.

Vink FJ, Meijer CJLM, Clifford GM, Poljak M, Oštrbenk A, Petry KU, Rothe B, Bonde J, Pedersen H, de Sanjosé S, Torres M, Del Pino M, Quint WGV, Cuschieri K, Boada EA, van Trommel NE, Lissenberg-Witte BI, Floore AN, Hesselink AT, Steenbergen RDM, Bleeker MCG, Heideman DAM.
FAM19A4/miR124-2 methylation in invasive cervical cancer: A retrospective cross-sectional worldwide study.
Int J Cancer. 2020 Aug 15;147(4):1215-1221. doi: 10.1002/ijc.32614. Epub 2019 Sep 9.

Vink FJ, Lissenberg-Witte B, Meijer CJLM, Berkhof J, Van Kemenade FJ, Siebers AG, Steenbergen RDM, Bleeker MCG, Heideman DAM.
FAM19A4/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort.
Clin Microbiol Infect. 2020 Mar 25. pii: S1198-743X(20)30163-4. doi: 10.1016/j.cmi.2020.03.018. [Epub ahead of print]

van der Zee RP, Richel O, van Noesel CJM, Ciocănea-Teodorescu I, van Splunter AP, Ter Braak TJ, Nathan M, Cuming T, Sheaff M, Kreuter A, Meijer CJLM, Quint WGV, de Vries HJC, Prins JM, Steenbergen RDM.
Cancer risk stratification of anal intraepithelial neoplasia in HIV-positive men by validated methylation markers associated with progression to cancer.
Clin Infect Dis. 2020 Apr 8:ciaa397. doi: 10.1093/cid/ciaa397. Online ahead of print.

   

2019

Babion, Iris ; De Strooper, Lise M A ; Luttmer, Roosmarijn ; Bleeker, Maaike C G ; Meijer, Chris J L M ; Heideman, Daniëlle A M ; Wilting, Saskia M ; Steenbergen, Renske D M. / Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease. In: Epigenetics. 2019 ; pp. 1-10.

Babion I, Jaspers A, van Splunter AP, van der Hoorn IAE, Wilting SM, Steenbergen RDM.
miR-9-5p Exerts a Dual Role in Cervical Cancer and Targets Transcription Factor TWIST1.
Cells. 2019 Dec 26;9(1). pii: E65. doi: 10.3390/cells9010065.

Van Bilsen WPH, Kovaleva A, Bleeker MCG, King AJ, Bruisten SM, Brokking W, De Vries HJC, Meijer CJLM, Schim Van Der Loeff MF.
HPV infections and flat penile lesions of the penis in men who have sex with men.
Papillomavirus Res. 2019 Dec;8:100173. doi: 10.1016/j.pvr.2019.100173. Epub 2019 Jun 18.

Brotherton JM, Winch KL, Chappell G, Banks C, Meijer D, Ennis S, Peterson K, Webby R, Whop LJ.
HPV vaccination coverage and course completion rates for Indigenous Australian adolescents, 2015.
Med J Aust. 2019 Jul;211(1):31-36. doi: 10.5694/mja2.50221. Epub 2019 Jun 9.

Dick, Stèfanie ; Kremer, Wieke W ; De Strooper, Lise M A ; Lissenberg-Witte, Birgit I ; Steenbergen, Renske D M ; Meijer, Chris J L M ; Berkhof, Johannes ; Heideman, Daniëlle A M. / Long-term CIN3+ risk of HPV positive women after triage with FAM19A4/miR124-2 methylation analysis. In: Gynecologic Oncology. 2019.

Floore A, Hesselink A, Oštrbenk A, Alcaniz E, Rothe B, Pedersen H, Torres Hortal M, Doorn S, Quint W, Petry KU, Poljak M, Cuschieri K, Bonde J, de Sanjosé S, Bleeker M, Heideman D. Intra- and inter-laboratory agreement of the FAM19A4/mir124-2 methylation test: Results from an international study.J Clin Lab Anal. 2019 Feb 13:e22854. doi: 10.1002/jcla.22854.

Heideman DAM, Xu L, Hesselink AT, Doorn S, Ejegod DM, Pedersen H, Quint WGV, Bonde J, Arbyn M. Clinical performance of the HPV-Risk assay on cervical samples in SurePath medium using the VALGENT-4 panel.
J Clin Virol. 2019 Oct 12;121:104201. doi: 10.1016/j.jcv.2019.104201. [Epub ahead of print]

Kremer, Wieke W. ; van Zummeren, Marjolein ; Breytenbach, Erika ; Richter, Karin L. ; Steenbergen, Renske D. M. ; Meijer, Chris J. L. M. ; Dreyer, Greta. / The use of molecular markers for cervical screening of women living with HIV in South Africa. In: AIDS. 2019 ; Vol. 33, No. 13. pp. 2035-2042.

Kremer WW, Berkhof J, Bleeker MC, Heideman DA, van Trommel NE, van Baal MW, Verhoeve HR, Meijer CJ, Kenter GG.
Role of FAM19A4/miR124-2 methylation analysis in predicting regression or non-regression of CIN2/3 lesions: a protocol of an observational longitudinal cohort study.
BMJ Open. 2019 Jul 9;9(7):e029017. doi: 10.1136/bmjopen-2019-029017.

Polman NJ, Ebisch RMF, Heideman DAM, Melchers WJG, Bekkers RLM, Molijn AC, Meijer CJLM, Quint WGV, Snijders PJF, Massuger LFAG, van Kemenade FJ, Berkhof J.Performance of human papillomavirus testing on self-collected versus clinician-collected samples for the detection of cervical intraepithelial neoplasia of grade 2 or worse: a randomised, paired screen-positive, non-inferiority trial. Lancet Oncol. 2019 Feb;20(2):229-238. doi: 10.1016/S1470-2045(18)30763-0.

Polman NJ, Snijders PJF, Kenter GG, Berkhof J, Meijer CJLM HPV-based cervical screening: Rationale, expectations and future perspectives of the new Dutch screening programme. Prev Med. 2019 Feb;119:108-117. doi: 10.1016/j.ypmed.2018.12.021.Review.PMID:30594536

Polman NJ, Veldhuijzen NJ, Heideman DAM, Snijders PJF, Meijer CJLM, Berkhof J.
Management of HPV-positive women in cervical screening using results from two consecutive screening rounds. Int J Cancer. 2019 May 1;144(9):2339-2346. doi: 10.1002/ijc.32004. PMID:30565673

Polman NJ, de Haan Y, Veldhuijzen NJ, Heideman DAM, de Vet HCW, Meijer CJLM, Massuger LFAG, van Kemenade FJ, Berkhof J.
Experience with HPV self-sampling and clinician-based sampling in women attending routine cervical screening in the Netherlands.
Prev Med. 2019 Aug;125:5-11. doi: 10.1016/j.ypmed.2019.04.025. Epub 2019 May 2.

Snoek BC, Splunter APV, Bleeker MCG, Ruiten MCV, Heideman DAM, Rurup WF, Verlaat W, Schotman H, Gent MV, Trommel NEV, Steenbergen RDM. Cervical cancer detection by DNA methylation analysis in urine. Sci Rep. 2019 Feb 28;9(1):3088. doi: 10.1038/s41598-019-39275-2.

Snoek BC, Verlaat W, Babion I, Novianti PW, van de Wiel MA, Wilting SM, van Trommel NE, Bleeker MCG, Massuger LFAG, Melchers WJG, Sie D, Heideman DAM, Snijders PJF, Meijer CJLM, Steenbergen RDM.Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer.Int J Cancer. 2019 Jan 15;144(2):372-379. doi: 10.1002/ijc.31855.

Snoek, Barbara C ; Splunter, Annina P van ; Bleeker, Maaike C G ; Ruiten, Maartje C van ; Heideman, Daniëlle A M ; Rurup, W Frederik ; Verlaat, Wina ; Schotman, Hans ; Gent, Mignon van ; Trommel, Nienke E van ; Steenbergen, Renske D M. / Cervical cancer detection by DNA methylation analysis in urine. In: Scientific Reports. 2019 ; Vol. 9, No. 1. pp. 3088.

Snoek, Barbara C ; Babion, Iris ; Koppers-Lalic, Danijela ; Pegtel, Dirk M ; Steenbergen, Renske Dm. / Altered microRNA processing proteins in HPV-induced cancers. In: Current opinion in virology. 2019 ; Vol. 39. pp. 23-32.

Vink, Frederique J ; Meijer, Chris J L M ; Clifford, Gary M ; Poljak, Mario ; Oštrbenk, Anja ; Petry, Karl Ulrich ; Rothe, Beate ; Bonde, Jesper ; Pedersen, Helle ; de Sanjosé, Silvia ; Torres, Montserrat ; Del Pino, Marta ; Quint, Wim G V ; Cuschieri, Kate ; Alcañiz Boada, Elia ; van Trommel, Nienke E ; Lissenberg-Witte, Birgit I ; Floore, Arno N ; Hesselink, Albertus T ; Steenbergen, Renske D M ; Bleeker, Maaike C G ; Heideman, Daniëlle A M. / FAM19A4/miR124-2 methylation in invasive cervical cancer : A retrospective cross-sectional worldwide study. In: International Journal of Cancer. 2019.

van der Weele P, Breeuwsma M, Donken R, van Logchem E, van Marm-Wattimena N, de Melker H, Meijer CJLM, King AJ. Effect of the bivalent HPV vaccine on viral load of vaccine and non-vaccine HPV types in incident clearing and persistent infections in young Dutch females. PLoS One. 2019 Mar 4;14(3):e0212927. doi: 10.1371/journal.pone.0212927. eCollection 2019.PMID: 30830913

van der Weele, Pascal ; King, Audrey J. ; Meijer, Chris J. L. M. ; Steenbergen, Renske D. M. / HPV16 variant analysis in primary and recurrent CIN2/3 lesions demonstrates presence of the same consensus variant. In: PAPILLOMAVIRUS RESEARCH. 2019 ; Vol. 7. pp. 168-172.

van der Zee, Ramon P. ; Richel, Olivier ; van Noesel, Carel J. M. ; Novianti, Putri W. ; Ciocanea-Teodorescu, Iuliana ; van Splunter, Annina P. ; Duin, Sylvia ; van den Berk, Guido E. L. ; Meijer, Chris J. L. M. ; Quint, Wim G. V. ; de Vries, Henry J. C. ; Prins, Jan M. ; Steenbergen, Renske D. M. / Host Cell Deoxyribonucleic Acid Methylation Markers for the Detection of High-grade Anal Intraepithelial Neoplasia and Anal Cancer. In: Clinical Infectious Diseases. 2019 ; Vol. 68, No. 7. pp. 1110-1117.

   

2018

Babion I, Snoek BC, Novianti PW, Jaspers A, Van Trommel N, Heideman DAM, Meijer CJLM, Snijders PJF, Steenbergen RDM, Wilting SM. Triage of high-risk HPV-positive women in population-based screening by miRNA expression analysis in cervical scrapes; a feasibility study. Clin Epigenetics. 2018 Jun 7;10:76. doi: 10.1186/s13148-018-0509-9.

Bonde J, Ejegod DM, Cuschieri K, Dillner J, Heideman DAM, Quint W, Pavon Ribas MA, Padalko E, Christiansen IK, Xu L, Arbyn M. The Valgent4 protocol: Robust analytical and clinical validation of 11 HPV assays with genotyping on cervical samples collected in SurePath medium.J Clin Virol. 2018 Sep 17;108:64-71. doi: 10.1016/j.jcv.2018.09.012. [Epub ahead of print] PMID:30253376

De Strooper LMA, Berkhof J, Steenbergen RDM, Lissenberg-Witte BI, Snijders PJF, Meijer CJLM, Heideman DAM.Cervical cancer risk in HPV-positive women after a negative FAM19A4/mir124-2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow-up. Int J Cancer. 2018 Apr 16. doi: 10.1002/ijc.31539. [Epub ahead of print] PMID:29663363

Donken R, King AJ, Bogaards JA, Woestenberg PJ, Meijer CJLM, de Melker HE. High Effectiveness of the Bivalent Human Papillomavirus (HPV) Vaccine Against Incident and Persistent HPV Infections up to 6 Years After Vaccination in Young Dutch Women. J Infect Dis. 2018 Apr 23;217(10):1579-1589. doi: 10.1093/infdis/jiy067.PMID:29409034

Hooi DJ, Lissenberg-Witte BI, de Koning MNC, Pinedo HM, Kenter GG, Meijer CJ, Quint WG. High prevalence of high-risk HPV genotypes other than 16 and 18 in cervical cancers of Curaçao: implications for choice of prophylactic HPV vaccine.Sex Transm Infect. 2018 Jun;94(4):263-267. doi: 10.1136/sextrans-2017-053109. Epub 2017 Oct 11. PMID:29021405

Hooi DJ, Lissenberg-Witte BI, Kenter G, de Koning MNC, Gomes Bravio I, Ardts K, Kleinmoedig S, Benita E, Pinedo HM, Berkhof J, Quint WGV, Meijer CJLM. Human papillomavirus (HPV) prevalence and associated risk factors in women from Curaçao. PLoS One. 2018 Jul 13;13(7):e0199624. doi: 10.1371/journal.pone.0199624. eCollection 2018.PMID:30005066

Hooi DJ, Quint WGV, Lissenberg-Witte BI, Kenter G, Pinedo HM, de Koning MNC, Meijer CJLM. Human papillomavirus (HPV) types prevalence in cervical samples of female sex-workers on Curaçao. Prev Med Rep. 2018 Jun 2;11:120-124. doi: 10.1016/j.pmedr.2018.06.001. eCollection 2018 Sep. PMID:29992082

Hooi DJ, Meijer CJLM, Witte BI, Bravio IG, Pinedo HM, Kenter GG. Supravaginal hysterectomy in Curaçao prevalence and impact on screening for cervical cancer. Prev Med Rep. 2017 Nov 8;8:238-241. doi: 10.1016/j.pmedr.2017.11.005. eCollection 2017 Dec. PMID: 29181295

Kremer WW, Van Zummeren M, Novianti PW, Richter KL, Verlaat W, Snijders PJF, Heideman DAM, Steenbergen RDM, Dreyer G, Meijer CJLM. Detection of hypermethylated genes as markers for cervical screening in women living with HIV. Journal of the International AIDS Society (in press).

Leeman A, Ebisch RMF, Kasius A, Bosgraaf RP, Jenkins D, van de Sandt MM, de Strooper LMA, Heideman DAM, Snijders PJF, Massuger LFAG, Bekkers RLM, Meijer CJLM, van Kemenade FJ, Quint WGV, Melchers WJG. Defining hrHPV genotypes in cervical intraepithelial neoplasia by laser capture microdissection supports reflex triage of self-samples using HPV16/18 and FAM19A4/miR124-2 methylation. Gynecol Oncol. 2018 Sep 12. pii: S0090-8258(18)31217-4. doi: 10.1016/j.ygyno.2018.09.006. [Epub ahead of print] PMID:30219239

Marra E, King A, van Logchem E, van der Weele P, Mooij SH, Heijman T, Meijer CJLM, Verhagen DWM, van der Sande MAB, Schim van der Loeff MF.Anal HPV 16 and 18 viral load: A comparison between HIV-negative and -positive MSM and association with persistence.J Med Virol. 2018 Jan;90(1):76-83. doi: 10.1002/jmv.24898. Epub 2017 Oct 17.PMID:28700080

Nauta IH, Rietbergen MM, van Bokhoven AAJD, Bloemena E, Lissenberg-Witte BI, Heideman DAM, Baatenburg de Jong RJ, Brakenhoff RH, Leemans CR. Evaluation of the eighth TNM classification on p16-positive oropharyngeal squamous cell carcinomas in the Netherlands and the importance of additional HPV DNA testing. Ann Oncol. 2018 May 1;29(5):1273-1279. doi: 10.1093/annonc/mdy060.PMID:29438466

Petry KU, Bollaerts K, Bonanni P, Stanley M, Drury R, Joura E, Kjaer SK, Meijer CJLM, Riethmuller D, Soubeyrand B, Van Damme P, Bosch X. Estimation of the individual residual risk of cervical cancer after vaccination with the nonavalent HPV vaccine. Hum Vaccin Immunother. 2018 Mar 19:1-7. doi: 10.1080/21645515.2018.1450125. [Epub ahead of print] PMID: 29553886

Rietbergen MM, van Bokhoven AAJD, Lissenberg-Witte BI, Heideman DAM, Leemans CR, Brakenhoff RH, Bloemena E. Epidemiologic associations of HPV-positive oropharyngeal cancer and (pre)cancerous cervical lesions. Int J Cancer. 2018 Jul 15;143(2):283-288. doi: 10.1002/ijc.31315. Epub 2018 Mar 2.PMID:29441569

Snoek BC, Verlaat W, Novianti PW, van de Wiel MA, Wilting SM, van Trommel NE, Massuger LFAG, Bekkers RLM, Melchers WJG, Sie D, Heideman DAM, Snijders PJF, Meijer CJLM, Steenbergen RDM. Genome-wide microRNA profiling of HPV-positive self-samples: Promising triage markers for early detection of cervical cancer. Int J Cancer Int J Cancer. 2018 Sep 7. doi: 10.1002/ijc.31855. [Epub ahead of print] PMID:30192375

Swarts DRA, Voorham QJM, van Splunter AP, Wilting SM, Sie D, Pronk D, van Beurden M, Heideman DAM, Snijders PJF, Meijer CJLM, Steenbergen RDM, Bleeker MCG. Molecular heterogeneity in HPV-dependent and -independent vulvar carcinogenesis. Cancer Med. 2018 Jul 20. doi: 10.1002/cam4.1633

Twisk DE, van der Sande MAB, van Eeden A, Heideman DAM, van der Klis FRM, de Vries HJC, Schim van der Loeff MF. Detection of Incident Anal High-Risk Human Papillomavirus DNA in Men Who Have Sex With Men: Incidence or Reactivation? J Infect Dis. 2018 Aug 24;218(7):1018-1026. doi: 10.1093/infdis/jiy276.PMID:29771378

Umulisa MC, Franceschi S, Baussano I, Tenet V, Uwimbabazi M, Rugwizangoga B, Heideman DAM, Uyterlinde AM, Darragh TM, Snijders PJF, Sayinzoga F, Clifford GM. Evaluation of human-papillomavirus testing and visual inspection for cervical cancer screening in Rwanda. BMC Womens Health. 2018 Apr 24;18(1):59. doi: 10.1186/s12905-018-0549-5.PMID:29699549

Verlaat W, Snoek BC, Heideman DAM, Wilting SM, Snijders PJF, Novianti PW, van Splunter AP, Peeters CFW, van Trommel NE, Massuger LFAG, Bekkers RLM, Melchers WJG, van Kemenade FJ, Berkhof J, van de Wiel MA, Meijer CJLM, Steenbergen RDM.Identification and Validation of a 3-Gene Methylation Classifier for HPV-Based Cervical Screening on Self-Samples.Clin Cancer Res. 2018 Apr 9. doi: 10.1158/1078-0432.CCR-17-3615. [Epub ahead of print] PMID:29632006

Verlaat W, van Leeuwen RW, Novianti PW, Schuuring E, Meijer CJLM, van der Zee AGJ, Snijders PJF, Heideman DAM, Steenbergen RDM*, Wisman GBA* (shared). Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer. Epigenetics. 2018 Aug 24:1-10. doi: 10.1080/15592294.2018.1507197. [Epub ahead of print] PMID: 30079796

de Vries HJC, Steenbergen RDM. The effect of ART on cervical cancer precursor lesions. Lancet HIV. 2018 Jan;5(1):e6-e8. doi: 10.1016/S2352-3018(17)30189-3. PMID: 29107564.

van der Weele P, Meijer CJLM, King AJ.High Whole-Genome Sequence Diversity of Human Papillomavirus Type 18 Isolates. Viruses. 2018 Feb 7;10(2). pii: E68. doi: 10.3390/v10020068. PMID:29414918

Woestenberg PJ, King AJ, van Benthem BHB, Donken R, Leussink S, van der Klis FRM, de Melker HE, van der Sande MAB, Hoebe CJPA, Bogaards JA; Medical Microbiological Laboratories and the Public Health Services .Bivalent Vaccine Effectiveness Against Type-Specific HPV Positivity: Evidence for Cross-Protection Against Oncogenic Types Among Dutch STI Clinic Visitors.J Infect Dis. 2018 Jan 4;217(2):213-222. doi: 10.1093/infdis/jix582. PMID:29140439

Van der Zee RP, Richel O, Van Noesel CJM, Novianti PW, Ciocanea-Teodorescu I, Van Splunter AP, Duin S, Van den Berk GEL, Meijer CJLM, Quint WGV, De Vries HJC, Prins JM, Steenbergen RDM. Host cell DNA methylation markers for the detection of high-grade anal intraepithelial neoplasia and anal cancer. Clin Infect Dis. 2018 Jul 27. doi: 10.1093/cid/ciy601. [Epub ahead of print] PMID: 30060049

Van Zummeren M, Leeman A, Bleeker MCG, Jenkins D, Van de Sandt M, Heideman DAM, Steenbergen RDM, Snijders PJF, Quin WGV, Berkhof J, Meijer CJLM. . A three-tiered score for Ki-67 and p16ink4a improves accuracy and reproducibility of grading CIN lesions. J Clin Pathol. 2018 Jul 16. pii: jclinpath-2018-205271. doi: 10.1136/jclinpath-2018-205271. [Epub ahead of print] PMID:30012698

Van Zummeren M, Kremer WK, Leeman A, Bleeker MCG, Jenkins D, Van de Sandt M, Doorbar J, Heideman DAM, Steenbergen RDM, Snijders PJF, Kenter GG, Quint WGV, Berkhof J, Meijer CJLM. HPV E4 expression and DNA hypermethylation of CADM1, MAL, and miR124-2 genes in cervical cancer and precursor lesions. Mod Pathol. 2018 Aug 22. doi: 10.1038/s41379-018-0101-z. [Epub ahead of print]PMID: 30135508
   

2017

Aromseree S, Middeldorp JM, Pientong C, van Eijndhoven M, Ramayanti O, Lougheed SM, Pegtel DM, Steenbergen RD, Ekalaksananan T. High Levels of EBV-Encoded RNA 1 (EBER1) Trigger Interferon and Inflammation-Related Genes in Keratinocytes Expressing HPV16 E6/E7. PLoS One. 2017 Jan 5;12(1):e0169290. doi: 10.1371/journal.pone.0169290. eCollection 2017. PMID: 28056059.

Babion I, Snoek BC, van de Wiel MA, Wilting SM, Steenbergen RDM. A Strategy to Find Suitable Reference Genes for miRNA Quantitative PCR Analysis and Its Application to Cervical Specimens. J Mol Diagn. 2017 Sep;19(5):625-637. doi: 10.1016/j.jmoldx.2017.04.010. PMID: 28826607

Te Beest DE, Mes SW, Wilting SM, Brakenhoff RH, van de Wiel MA. Improved high-dimensional prediction with Random Forests by the use of co-data. BMC Bioinformatics. 2017 Dec 28;18(1):584. doi: 10.1186/s12859-017-1993-1. PMID: 29281963.

Correa RM, Vladimirsky S, Heideman DA, Coringrato M, Abeldaño A, Olivares L, Del Aguila R, Alonio LV, Snijders PJ, Picconi MA. Cutaneous human papillomavirus genotypes in different kinds of skin lesions in Argentina. J Med Virol. 2017 Feb;89(2):352-357. doi: 10.1002/jmv.24631. Epub 2016 Jul 27. PMID: 27420901.

Donken R, Schurink-Van't Klooster TM, Schepp RM, van der Klis FR, Knol MJ, Meijer CJ, de Melker HE. Immune Responses After 2 Versus 3 Doses of HPV Vaccination up to 4½ Years After Vaccination: An Observational Study Among Dutch Routinely Vaccinated Girls. J Infect Dis. 2017 Feb 1;215(3):359-367. doi: 10.1093/infdis/jiw588. PMID: 28011916

Ebisch RM, van der Horst J, Hermsen M, Rijstenberg LL, Vedder JE, Bulten J, Bosgraaf RP, Verhoef VM, Heideman DA, Snijders PJ, Meijer CJ, van Kemenade FJ, Massuger LF, Melchers WJ, Bekkers RL, Siebers AG. Evaluation of p16/Ki-67 dual-stained cytology as triage test for high-risk human papillomavirus-positive women. Mod Pathol. 2017 Jul;30(7):1021-1031. doi: 10.1038/modpathol.2017.16. Epub 2017 Mar 17. PMID: 28304400.

Hooi DJ, Meijer CJLM, Witte BI, Bravio IG, Pinedo HM, Kenter GG. Supravaginal hysterectomy in Curaçao prevalence and impact on screening for cervical cancer. Prev Med Rep. 2017 Nov 8;8:238-241. doi: 10.1016/j.pmedr.2017.11.005. eCollection 2017 Dec. PMID: 29181295

Hooi DJ, Lissenberg-Witte BI, de Koning MNC, Pinedo HM, Kenter GG, Meijer CJLM, Quint WG. High prevalence of high-risk HPV genotypes other than 16 and 18 in cervical cancers of Curaçao: implications for choice of prophylactic HPV vaccine. Sex Transm Infect. 2017 Oct 11. pii: sextrans-2017-053109. doi: 10.1136/sextrans-2017-053109. [Epub ahead of print]. PMID: 29021405

Hubers AJ, Heideman DA, Duin S, Witte BI, de Koning HJ, Groen HJ, Prinsen CF, Bolijn AS, Wouters M, van der Meer SE, Steenbergen RD, Snijders PJ, Uyterlinde A, Berkhof H, Smit EF, Thunnissen E. DNA hypermethylation analysis in sputum of asymptomatic subjects at risk for lung cancer participating in the NELSON trial: argument for maximum screening interval of 2 years. J Clin Pathol. 2017 Mar;70(3):250-254. doi: 10.1136/jclinpath-2016-203734. Epub 2016 Aug 5. PMID: 27496969.

Khan S, Oosterhuis K, Wunderlich K, Bunnik EM, Bhaggoe M, Boedhoe S, Karia S, Steenbergen RD, Bosch L, Serroyen J, Janssen S, Schuitemaker H, Vellinga J, Scheper G, Zahn R, Custers J. Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease. Int J Cancer. 2017 Jul 15;141(2):393-404. doi: 10.1002/ijc.30679. Epub 2017 Apr 24. PMID: 28263390.

McDonald SA, Qendri V, Berkhof J, de Melker HE, Bogaards JA. Disease burden of human papillomavirus infection in the Netherlands, 1989-2014: the gap between females and males is diminishing. Cancer Causes Control. 2017 Mar;28(3):203-214. doi: 10.1007/s10552-017-0870-6. Epub 2017 Feb 17. PMID: 28213874.

Meijer CJLM, Steenbergen RDM. Gynaecological cancer: Novel molecular subtypes of cervical cancer - potential clinical consequences. Nat Rev Clin Oncol. 2017 Jul;14(7):397-398. doi: 10.1038/nrclinonc.2017.52. Epub 2017 Apr 11. PMID: 28397825.

Meijer CJLM, Snijders PJF. Human Papillomavirus Triage of Women With Atypical Squamous Cells of Undetermined Significance-Reduction of Overtreatment Needed. JAMA Oncol. 2017 Oct 1;3(10):1310-1311. doi: 10.1001/jamaoncol.2017.1522. PMID: 28654967.

Miok V, Wilting SM, van Wieringen WN. Ridge estimation of the VAR(1) model and its time series chain graph from multivariate time-course omics data. Biom J. 2017 Jan;59(1):172-191. doi: 10.1002/bimj.201500269. Epub 2016 Nov 7. PMID: 27902843.

Novianti PW, Snoek BC, Wilting SM, van de Wiel MA. Better diagnostic signatures from RNAseq data through use of auxiliary co-data. Bioinformatics. 2017 Jan 10. pii: btw837. doi: 10.1093/bioinformatics/btw837. [Epub ahead of print]. PMID: 28073760.

Polman NJ, Uijterwaal MH, Witte BI, Berkhof J, van Kemenade FJ, Spruijt JW, van Baal WM, Graziosi PG, van Dijken DK, Verheijen RH, Helmerhorst TJ, Steenbergen RD, Heideman DA, Ridder R, Snijders PJ, Meijer CJ. Good performance of p16/ki-67 dual-stained cytology for surveillance of women treated for high-grade CIN. Int J Cancer. 2017 Jan 15;140(2):423-430. doi: 10.1002/ijc.30449. Epub 2016 Oct 11. PMID: 27677098.

Polman NJ, Veldhuijzen NJ, Heideman DAM, Snijders PJF, Meijer CJLM, Berkhof J. HPV-positive women with normal cytology remain at increased risk of CIN3 after a negative repeat HPV test. Br J Cancer. 2017 Nov 7;117(10):1557-1561. doi: 10.1038/bjc.2017.309. Epub 2017 Sep 7. PMID: 28881359.

Polman NJ, Oštrbenk A, Xu L, Snijders PJF, Meijer CJLM, Poljak M, Heideman DAM, Arbyn M. Evaluation of the Clinical Performance of the HPV-Risk Assay Using the VALGENT-3 Panel. J Clin Microbiol. 2017 Dec;55(12):3544-3551. doi: 10.1128/JCM.01282-17. Epub 2017 Oct 11. PMID: 29021152

Qendri V, Bogaards JA, Berkhof J. Health and Economic Impact of a Tender-Based, Sex-Neutral Human Papillomavirus 16/18 Vaccination Program in the Netherlands. J Infect Dis. 2017 Jul 15;216(2):210-219. doi: 10.1093/infdis/jix272. PMID: 28586466

Sarkisjan D, Steenbergen RD, Cloos J, Peters GJ. Re-emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects. In: Ueda T. (eds) Chemotherapy for Leukemia. Springer, Singapore. 2017:311-326.

Suijkerbuijk AW, Donken R, Lugnér AK, de Wit GA, Meijer CJ, de Melker HE, Bogaards JA. The whole story: a systematic review of economic evaluations of HPV vaccination including non-cervical HPV-associated diseases. Expert Rev Vaccines. 2017 Apr;16(4):361-375. doi: 10.1080/14760584.2017.1256778. Epub 2016 Nov 24. PMID: 27807989.

Veluchamy JP, Lopez-Lastra S, Spanholtz J, Bohme F, Kok N, Heideman DA, Verheul HM, Di Santo JP, de Gruijl TD, van der Vliet HJ. In Vivo Efficacy of Umbilical Cord Blood Stem Cell-Derived NK Cells in the Treatment of Metastatic Colorectal Cancer. Front Immunol. 2017 Feb 6;8:87. doi: 10.3389/fimmu.2017.00087. eCollection 2017. PMID: 28220124.

Tshomo U, Franceschi S, Tshokey T, Tobgay T, Baussano I, Tenet V, Snijders PJ, Gheit T, Tommasino M, Vorsters A, Clifford GM. Evaluation of the performance of Human Papillomavirus testing in paired urine and clinician-collected cervical samples among women aged over 30 years in Bhutan. Virol J. 2017 Apr 8;14(1):74. doi: 10.1186/s12985-017-0744-2. PMID: 28390433

Tshomo U, Franceschi S, Tshokey T, Tobgay T, Baussano I, Tenet V, Heideman DAM, Snijders PJF, Clifford GM. Evaluation of cytology versus human papillomavirus-based cervical cancer screening algorithms in Bhutan. Oncotarget. 2017 Aug 2;8(42):72438-72446. doi: 10.18632/oncotarget.19783. eCollection 2017 Sep 22. PMID: 29069800.

Veldhuijzen NJ, Polman NJ, Snijders PJF, Meijer CJLM, Berkhof J. Stratifying HPV-positive women for CIN3+ risk after one and two rounds of HPV-based screening. Int J Cancer. 2017 Oct 15;141(8):1551-1560. doi: 10.1002/ijc.30865. Epub 2017 Jul 18. PMID: 28670823

Veluchamy JP, Heeren AM, Spanholtz J, van Eendenburg JD, Heideman DA, Kenter GG, Verheul HM, van der Vliet HJ, Jordanova ES, de Gruijl TD. High-efficiency lysis of cervical cancer by allogeneic NK cells derived from umbilical cord progenitors is independent of HLA status. Cancer Immunol Immunother. 2017 Jan;66(1):51-61. doi: 10.1007/s00262-016-1919-1. Epub 2016 Oct 25. PMID: 27783105.

 

Verlaat W, Snijders PJ, Novianti PW, Wilting SM, De Strooper LM, Trooskens G, Vandersmissen J, Van Criekinge W, Wisman GB, Meijer CJ, Heideman DA, Steenbergen RD. Genome-wide DNA methylation profiling reveals methylation markers associated with 3q gain for detection of cervical pre-cancer and cancer. Clin Cancer Res. 2017 Jul 15;23(14):3813-3822. doi: 10.1158/1078-0432.CCR-16-2641. Epub 2017 Jan 24. PMID: 28119363.

van der Weele P, Meijer CJLM, King AJ. Whole-Genome Sequencing and Variant Analysis of Human Papillomavirus 16 Infections. J Virol. 2017 Sep 12;91(19). pii: e00844-17. doi: 10.1128/JVI.00844-17. Print 2017 Oct 1. PMID: 28701400

van der Wekken AJ, Kuiper JL, Saber A, Terpstra MM, Wei J, Hiltermann TJN, Thunnissen E, Heideman DAM, Timens W, Schuuring E, Kok K, Smit EF, van den Berg A, Groen HJM. Overall survival in EGFR mutated non-small-cell lung cancer patients treated with afatinib after EGFR TKI and resistant mechanisms upon disease progression. PLoS One. 2017 Aug 30;12(8):e0182885. doi: 10.1371/journal.pone.0182885. eCollection 2017. PMID: 28854272

Wentzensen N, Arbyn M, Berkhof J, Bower M, Canfell K, Einstein M, Farley C, Monsonego J, Franceschi S. Eurogin 2016 Roadmap: how HPV knowledge is changing screening practice. Int J Cancer. 2017 May 15;140(10):2192-2200. doi: 10.1002/ijc.30579. Epub 2017 Jan 11. Review. PMID: 28006858

Van Zummeren M, Kremer WW, Van Aardt MC, Breytenbach E, Richter KL, Rozendaal L, Witte BI, De Strooper LMA, Hesselink AT, Heideman DAM, Snijders PJF, Steenbergen RDM, Dreyer G, Meijer CJLM. Selection of women at risk for cervical cancer in an HIV-infected South African population. AIDS. 2017 Sep 10;31(14):1945-1953. doi: 10.1097/QAD.0000000000001583. PMID: 28692545.

2016

van Baars R, van der Marel J, Snijders PJ, Rodriquez-Manfredi A, Ter Harmsel B, van den Munckhof HA, Ordi J, Del Pino M, van de Sandt MM, Wentzensen N, Meijer CJ, Quint WG. CADM1 and MAL methylation status in cervical scrapes is representative of the most severe underlying lesion in women with multiple cervical biopsies. Int J Cancer. 2016 Jan 15;138(2):463-71. doi: 10.1002/ijc.29706. Epub 2015 Aug 14.

Bleeker MC, Visser PJ, Overbeek LI, van Beurden M, Berkhof J. Lichen Sclerosus: Incidence and Risk of Vulvar Squamous Cell Carcinoma. Cancer Epidemiol Biomarkers Prev. 2016 Aug;25(8):1224-30. doi: 10.1158/1055-9965.EPI-16-0019. Epub 2016 Jun 2

Bosch FX, Robles C, Díaz M, Arbyn M, Baussano I, Clavel C, Ronco G, Dillner J, Lehtinen M, Petry KU, Poljak M, Kjaer SK, Meijer CJ, Garland SM, Salmerón J, Castellsagué X, Bruni L, de Sanjosé S, Cuzick J. HPV-FASTER: broadening the scope for prevention of HPV-related cancer. Nat Rev Clin Oncol. 2016 Feb;13(2):119-32. doi: 10.1038/nrclinonc.2015.146. Epub 2015 Sep 1. Review.

Clifford GM, Vaccarella S, Franceschi S, Tenet V, Umulisa MC, Tshomo U, Dondog B, Vorsters A, Tommasino M, Heideman DA, Snijders PJ, Gheit T.Comparison of two widely-used HPV detection and genotyping methods: GP5+/6+ PCR followed by reverse line blot hybridization and multiplex type-specific E7 PCR. J Clin Microbiol. 2016 Aug;54(8):2031-8. doi: 10.1128/JCM.00618-16. Epub 2016 May 25.

de Cuba EM, Snaebjornsson P, Heideman DA, van Grieken NC, Bosch LJ, Fijneman RJ, Belt E, Bril H, Stockmann HB, Hooijberg E, Punt CJ, Koopman M, Nagtegaal ID, Coupé VH, Carvalho B, Meijer GA. Prognostic value of BRAF and KRAS mutation status in stage II and III microsatellite instable colon cancers. Int J Cancer. 2016 Mar 1;138(5):1139-45. doi: 10.1002/ijc.29855. Epub 2015 Oct 23.

Van Damme P, Meijer CJ, Kieninger D, Schuyleman A, Thomas S, Luxembourg A, Baudin M. A phase III clinical study to compare the immunogenicity and safety of the 9-valent and quadrivalent HPV vaccines in men. Vaccine. 2016 Jul 29;34(35):4205-12. doi: 10.1016/j.vaccine.2016.06.056. Epub 2016 Jun 25.

Van Damme P, Bonanni P, Bosch FX, Joura E, Kjaer SK, Meijer CJ, Petry KU, Soubeyrand B, Verstraeten T, Stanley M. Use of the nonavalent HPV vaccine in individuals previously fully or partially vaccinated with bivalent or quadrivalent HPV vaccines. Vaccine. 2016 Feb 3;34(6):757-61. doi: 10.1016/j.vaccine.2015.12.063. Epub 2016 Jan 6.

Van Damme P, Bonanni P, Bosch FX, Joura E, Kjaer SK, Meijer CJ, Petry KU, Soubeyrand B, Verstraeten T, Stanley M. Corrigendum to "Use of the nonavalent HPV vaccine in individuals previously fully or partially vaccinated with bivalent or quadrivalent HPV vaccines" [Vaccine 34 (2016) 757-761]. Vaccine. 2016 Sep 7;34(39):4759-4760. doi: 10.1016/j.vaccine.2016.07.035. Epub 2016 Jul 25.

Dijkstra MG, van Zummeren M, Rozendaal L, van Kemenade FJ, Helmerhorst TJ, Snijders PJ, Meijer CJ, Berkhof J. Safety of extending screening intervals beyond five years in cervical screening programmes with testing for high risk human papillomavirus: 14 year follow-up of population based randomised cohort in the Netherlands. BMJ. 2016 Oct 4;355:i4924. doi: 10.1136/bmj.i4924.

Donken R, Bogaards JA, van der Klis FR, Meijer CJ, de Melker HE. An exploration of individual- and population-level impact of the 2-dose HPV vaccination schedule in pre-adolescent girls. Hum Vaccin Immunother. 2016 Jun 2;12(6):1381-93. doi: 10.1080/21645515.2016.1160978. Epub 2016 May 12.

Ebisch RM, de Kuyper-de Ridder GM, Bosgraaf RP, Massuger LF, IntHout J, Verhoef VM, Heideman DA, Snijders PJ, Meijer CJ, van Kemenade FJ, Bulten J, Siebers AG, Bekkers RL, Melchers WJ.The clinical value of HPV genotyping in triage of women with high-risk-HPV-positive self-samples.Int J Cancer. 2016 Aug 1;139(3):691-9. doi: 10.1002/ijc.30090.

Franceschi S, Chantal Umulisa M, Tshomo U, Gheit T, Baussano I, Tenet V, Tshokey T, Gatera M, Ngabo F, Van Damme P, Snijders PJ, Tommasino M, Vorsters A, Clifford GM. Urine testing to monitor the impact of HPV vaccination in Bhutan and Rwanda. Int J Cancer. 2016 Aug 1;139(3):518-26. doi: 10.1002/ijc.30092.

Geraets DT, Cuschieri K, de Koning MN, van Doorn LJ, Snijders PJ, Meijer CJ, Quint WG, Arbyn M. Correction for Geraets et al., Clinical Evaluation of a GP5+/6+-Based Luminex Assay Having Full High-Risk Human Papillomavirus Genotyping Capability and an Internal Control. J Clin Microbiol. 2016 Jul;54(7):1927. doi: 10.1128/JCM.00753-16.

Giorgi Rossi P, Ronco G, Dillner J, Elfström KM, Snijders PJ, Arbyn M, Berkhof J, Carozzi F, Del Mistro A, De Sanjosè S, Bosch X, Petry KU, Poljak M, Naldoni C, Meijer CJ; Comparing Health Services Interventions for the Prevention of HPV-Related Cancer Consortium; New Technologies for Cervical Cancer Group. Why follow-back studies should be interpreted cautiously: The case of an HPV-negative cervical lesion. Cancer Cytopathol. 2016 Jan;124(1):66-7. doi: 10.1002/cncy.21622. Epub 2015 Sep 10. No abstract available

Hesselink AT, Sahli R, Berkhof J, Snijders PJ, van der Salm ML, Agard D, Bleeker MC, Heideman DA. Clinical validation of Anyplex™ II HPV HR Detection according to the guidelines for HPV test requirements for cervical cancer screening. J Clin Virol. 2016 Mar;76:36-9. doi: 10.1016/j.jcv.2016.01.009.

Kuiper JL, Hashemi SM, Thunnissen E, Snijders PJ, Grünberg K, Bloemena E, Sie D, Postmus PE, Heideman DA, Smit EF. Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment. Br J Cancer. 2016 Dec 6;115(12):1504-1512. doi: 10.1038/bjc.2016.372. Epub 2016 Nov 22.

Luttmer R, Dijkstra MG, Snijders PJ, Hompes PG, Pronk DT, Hubeek I, Berkhof J, Heideman DA, Meijer CJ. Presence of human papillomavirus in semen in relation to semen quality.
Hum Reprod. 2016 Feb;31(2):280-6. doi: 10.1093/humrep/dev317. Epub 2016 Jan 2.

Luttmer R, Dijkstra MG, Snijders PJ, Berkhof J, van Kemenade FJ, Rozendaal L, Helmerhorst TJ, Verheijen RH, Ter Harmsel WA, van Baal WM, Graziosi PG, Quint WG, Spruijt JW, van Dijken DK, Heideman DA, Meijer CJ. p16/Ki-67 dual-stained cytology for detecting cervical (pre)cancer in a HPV-positive gynecologic outpatient population.
Mod Pathol. 2016 Aug;29(8):870-8. doi: 10.1038/modpathol.2016.80. Epub 2016 May 6.

Luttmer R, De Strooper LM, Berkhof J, Snijders PJ, Dijkstra MG, Uijterwaal MH, Steenbergen RD, van Kemenade FJ, Rozendaal L, Helmerhorst TJ, Verheijen RH, Ter Harmsel WA, Van Baal WM, Graziosi PG, Quint WG, Heideman DA, Meijer CJ. Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study). Int J Cancer. 2016 Feb 15;138(4):992-1002. doi: 10.1002/ijc.29824. Epub 2015 Sep 14.

Luttmer R, De Strooper LM, Steenbergen RD, Berkhof J, Snijders PJ, Heideman DA, Meijer CJ. Management of high-risk HPV-positive women for detection of cervical (pre)cancer.
Expert Rev Mol Diagn. 2016 Sep;16(9):961-74. doi: 10.1080/14737159.2016.1217157. Epub 2016 Aug 5.

Luttmer R, De Strooper LM, Dijkstra MG, Berkhof J, Snijders PJ, Steenbergen RD, van Kemenade FJ, Rozendaal L, Helmerhorst TJ, Verheijen RH, Ter Harmsel WA, van Baal WM, Graziosi PG, Quint WG, Spruijt JW, van Dijken DK, Heideman DA, Meijer CJ. FAM19A4 methylation analysis in self-samples compared with cervical scrapes for detecting cervical (pre)cancer in HPV-positive women. Br J Cancer. 2016 Aug 23;115(5):579-87. doi: 10.1038/bjc.2016.200. Epub 2016 Jul 14.

Mooij SH, van Santen DK, Geskus RB, van der Sande MA, Coutinho RA, Stolte IG, Snijders PJ, Meijer CJ, Speksnijder AG, de Vries HJ, King AJ, van Eeden A, van der Loeff MF. The effect of HIV infection on anal and penile human papillomavirus incidence and clearance: a cohort study among MSM. AIDS. 2016 Jan 2;30(1):121-32. doi: 10.1097/QAD.0000000000000909.

Ngabo F, Franceschi S, Baussano I, Umulisa MC, Snijders PJ, Uyterlinde AM, Lazzarato F, Tenet V, Gatera M, Binagwaho A, Clifford GM. Human papillomavirus infection in Rwanda at the moment of implementation of a national HPV vaccination programme.BMC Infect Dis. 2016 May 24;16(1):225. doi: 10.1186/s12879-016-1539-6.

Nilsson RJ, Karachaliou N, Berenguer J, Gimenez-Capitan A, Schellen P, Teixido C, Tannous J, Kuiper JL, Drees E, Grabowska M, van Keulen M, Heideman DA, Thunnissen E, Dingemans AM, Viteri S, Tannous BA, Drozdowskyj A, Rosell R, Smit EF, Wurdinger T. Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer. Oncotarget. 2016 Jan 5;7(1):1066-75. doi: 10.18632/oncotarget.6279.

Punt S, Dronkers EA, Welters MJ, Goedemans R, Koljenović S, Bloemena E, Snijders PJ, Gorter A, van der Burg SH, Baatenburg de Jong RJ, Jordanova ES. A beneficial tumor microenvironment in oropharyngeal squamous cell carcinoma is characterized by a high T cell and low IL-17(+) cell frequency. Cancer Immunol Immunother. 2016 Apr;65(4):393-403. doi: 10.1007/s00262-016-1805-x.

Rossi PG, Ronco G, Dillner J, Elfström KM, Snijders PJ, Arbyn M, Berkhof J, Carozzi F, Del Mistro A, De Sanjosè S, Bosch X, Petry KU, Poljak M, Naldoni C, Meijer CJ; Comparing Health Services Interventions for the Prevention of HPV-Related Cancer Consortium.; New Technologies for Cervical Cancer Group. Cancer Cytopathol. 2016 Jan;124(1):66-7. doi: 10.1002/cncy.21622. Epub 2015 Sep 10.

Schütze DM, Krijgsman O, Snijders PJ, Ylstra B, Weischenfeldt J, Mardin BR, Stütz AM, Korbel JO, de Winter JP, Meijer CJ, Quint WG, Bosch L, Wilting SM, Steenbergen RD. Immortalization capacity of HPV types is inversely related to chromosomal instability.Oncotarget. 2016 Jun 21;7(25):37608-37621. doi: 10.18632/oncotarget.8058.

Senkomago V, Backes DM, Hudgens MG, Poole C, Meshnick SR, Agot K, Moses S, Snijders PJ, Meijer CJ, Hesselink AT, Schlecht NF, Bailey RC, Smith JS. Higher HPV16 and HPV18 Penile Viral Loads Are Associated With Decreased Human Papillomavirus Clearance in Uncircumcised Kenyan Men. Sex Transm Dis. 2016 Sep;43(9):572-8. doi: 10.1097/OLQ.0000000000000500.

van der Sluis WB, Buncamper ME, Bouman MB, Neefjes-Borst EA, Heideman DA, Steenbergen RD, Mullender MG. Symptomatic HPV-related neovaginal lesions in transgender women: case series and review of literature. Sex Transm Infect. 2016 Mar 24. pii: sextrans-2015-052456. doi: 10.1136/sextrans-2015-052456. [Epub ahead of print]

van der Sluis WB, Buncamper ME, Bouman MB, Elfering L, Özer M, Bogaarts M, Steenbergen RD, Heideman DA, Mullender MG. Prevalence of Neovaginal High-Risk Human Papillomavirus Among Transgender Women in The Netherlands. Sex Transm Dis. 2016 Aug;43(8):503-5. doi: 10.1097/OLQ.0000000000000476.

De Strooper LM, Verhoef VM, Berkhof J, Hesselink AT, de Bruin HM, van Kemenade FJ, Bosgraaf RP, Bekkers RL, Massuger LF, Melchers WJ, Steenbergen RD, Snijders PJ, Meijer CJ, Heideman DA. Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women.Gynecol Oncol. 2016 May;141(2):341-7. doi: 10.1016/j.ygyno.2016.02.012.

Turksma AW, Coupé VM, Shamier MC, Lam KL, de Weger VA, Belien JA, van den Eertwegh AJ, Meijer GA, Meijer CJ, Hooijberg E. Extent and Location of Tumor-Infiltrating Lymphocytes in Microsatellite-Stable Colon Cancer Predict Outcome to Adjuvant Active Specific Immunotherapy. Clin Cancer Res. 2016 Jan 15;22(2):346-56. doi: 10.1158/1078-0432.CCR-13-2462. Epub 2015 Sep 29.

Uijterwaal MH, van Zummeren M, Kocken M, Luttmer R, Berkhof J, Witte BI, van Baal WM, Graziosi GC, Verheijen RH, Helmerhorst TJ, van Dijken DK, Spruijt JW, van Kemenade FJ, Fransen-Daalmeijer N, Bekker-Lettink M, Heideman DA, Snijders PJ, Steenbergen RD, Meijer CJ. Performance of CADM1/MAL-methylation analysis for monitoring of women treated for high-grade CIN. Gynecol Oncol. 2016 Oct;143(1):135-42. doi: 10.1016/j.ygyno.2016.07.089. Epub 2016 Jul 16.

Valdano MB, Cavatorta AL, Morale MG, Marziali F, de Souza Lino V, Steenbergen RD, Boccardo E, Gardiol D.Disc large 1 expression is altered by human papillomavirus E6/E7 proteins in organotypic cultures of human keratinocytes. J Gen Virol. 2016 Feb;97(2):453-62. doi: 10.1099/jgv.0.000364.

Veluchamy JP, Spanholtz J, Tordoir M, Thijssen VL, Heideman DA, Verheul HM, de Gruijl TD, van der Vliet HJ. Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer. PLoS One. 2016 Jun 17;11(6):e0157830. doi: 10.1371/journal.pone.0157830. eCollection 2016.

Wang R, van Leeuwen RW, Boers A, Klip HG, de Meyer T, Steenbergen RD, van Criekinge W, van der Zee AG, Schuuring E, Wisman GB. Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma. Oncotarget. 2016 Dec 6;7(49):80735-80750. doi: 10.18632/oncotarget.12598.

van der Weele P, van Logchem E, Wolffs P, van den Broek I, Feltkamp M, de Melker H, Meijer CJ, Boot H, King AJ. Correlation between viral load, multiplicity of infection, and persistence of HPV16 and HPV18 infection in a Dutch cohort of young women. J Clin Virol. 2016 Oct;83:6-11. doi: 10.1016/j.jcv.2016.07.020. Epub 2016 Aug 4.

van de Wiel MA, Lien TG, Verlaat W, van Wieringen WN, Wilting SM. Better prediction by use of co-data: adaptive group-regularized ridge regression. Stat Med. 2016 Feb 10;35(3):368-81. doi: 10.1002/sim.6732. Epub 2015 Sep 13.

Wilting SM, Miok V, Jaspers A, Boon D, Sørgård H, Lando M, Snoek BC, van Wieringen WN, Meijer CJ, Lyng H, Snijders PJ, Steenbergen RD. Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence. Oncotarget. 2016 Jul 12;7(28):43805-43819. doi: 10.18632/oncotarget.9698.

Wilting SM, Steenbergen RDM. Molecular events leading to HPV-induced high grade neoplasia (review). Papillomavirus Research, Volume 2, December 2016, Pages 85-88
2016

 

 

2015

Arbyn M, Snijders PJ, Meijer CJ, Berkhof J, Cuschieri K, Kocjan BJ, Poljak M. Which high-risk HPV assays fulfil criteria for use in primary cervical cancer screening? Clin Microbiol Infect. 2015 Sep;21(9):817-26. doi: 10.1016/j.cmi.2015.04.015. Epub 2015 May 1. Review.

Bosgraaf RP, Verhoef VM, Massuger LF, Siebers AG, Bulten J, de Kuyper-de Ridder GM, Meijer CJ, Snijders PJ, Heideman DA, IntHout J, van Kemenade FJ, Melchers WJ, Bekkers RL. Comparative performance of novel self-sampling methods in detecting high-risk human papillomavirus in 30,130 women not attending cervical screening. Int J Cancer. 2015 Feb 1;136(3):646-55. doi:
10.1002/ijc.29026. Epub 2014 Jun 26. PubMed PMID: 24923998.

Bosch FX, Robles C, Díaz M, Arbyn M, Baussano I, Clavel C, Ronco G, Dillner J, Lehtinen M, Petry KU, Poljak M, Kjaer SK, Meijer CJ, Garland SM, Salmerón J, Castellsagué X, Bruni L, de Sanjosé S, Cuzick J. HPV-FASTER: broadening the scope for prevention of HPV-related cancer. Nat Rev Clin Oncol. 2015 Sep 1. doi: 10.1038/nrclinonc.2015.146. [Epub ahead of print] Review.

De Vuyst H, Franceschi S, Plummer M, Mugo NR, Sakr SR, Meijer CJ, Heideman DA, Tenet V, Snijders PJ, Hesselink AT, Chung MH. Methylation Levels of CADM1, MAL, and MIR124-2 in Cervical Scrapes for Triage of HIV-Infected, High-Risk HPV-Positive Women in Kenya. J Acquir Immune Defic Syndr. 2015 Nov 1;70(3):311-8.

Djajadiningrat RS, Jordanova ES, Kroon BK, van Werkhoven E, de Jong J, Pronk DT, Snijders PJ, Horenblas S, Heideman DA. Human papillomavirus prevalence in invasive penile cancer and association with clinical outcome. J Urol. 2015 Feb;193(2):526-31. doi: 10.1016/j.juro.2014.08.087. Epub 2014 Aug 21. PubMed PMID: 25150641.

Donken R, Knol MJ, Bogaards JA, van der Klis FR, Meijer CJ, de Melker HE. Inconclusive evidence for non-inferior immunogenicity of two- compared with three-dose HPV immunization schedules in preadolescent girls: A systematic review and meta-analysis. J Infect. 2015 Jul;71(1):61-73.

Geraets DT, Cuschieri K, de Koning MN, van Doorn LJ, Snijders PJ, Meijer CJ, Quint WG, Arbyn M. Clinical evaluation of a GP5+/6+-based Luminex assay having full high-risk HPV genotyping capability and an internal control. J Clin Microbiol. 2014 Sep 10. pii: JCM.01962-14. [Epub ahead of print] PubMed PMID:25210073.

Giorgi-Rossi P, Arbyn M, Meijer CJ. Cervical cancer screening by human papillomavirus testing followed by cytology triage. JAMA Intern Med. 2015 Jun;175(6):1068.

Giorgi Rossi P, Ronco G, Dillner J, Elfström KM, Snijders PJ, Arbyn M, Berkhof J, Carozzi F, Del Mistro A, De Sanjosè S, Bosch X, Petry KU, Poljak M, Naldoni C, Meijer CJ; Comparing Health Services Interventions for the Prevention of HPV-Related Cancer Consortium and the New Technologies for Cervical Cancer Group. Why follow-back studies should be interpreted cautiously: The case of an HPV-negative cervical lesion. Cancer Cytopathol. 2015 Sep 10. doi: 10.1002/cncy.21622. [Epub ahead of print]

Lando M, Fjeldbo CS, Wilting SM, Snoek B, Aarnes EK, Forsberg MF, Kristensen GB, Steenbergen RD,
Lyng H. Interplay between promoter methylation and chromosomal loss in gene silencing at 3p11-p14 in cervical cancer. Epigenetics 2015; 10(10):970-80. doi: 10.1080/15592294.2015.1085140.

Louwers JA, Zaal A, Kocken M, Berkhof J, Papagiannakis E, Snijders PJ, Meijer CJ, Verheijen RH. The performance of Dynamic Spectral Imaging colposcopy depends on indication for referrals. Gynecol Oncol. 2015 Oct 14. pii: S0090-8258(15)30158-X. doi: 10.1016/j.ygyno.2015.10.009. [Epub ahead of print]

Luttmer R, De Strooper LM, Berkhof J, Snijders PJ, Dijkstra MG, Uijterwaal MH, Steenbergen RD, van Kemenade FJ, Rozendaal L, Helmerhorst TJ, Verheijen RH, Ter Harmsel WA, Van Baal WM, Graziosi PG, Quint WG, Heideman DA, Meijer CJ. Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study). Int J Cancer. 2015 Aug 28. doi: 10.1002/ijc.29824. [Epub ahead of print] PubMed PMID: 26317579.

Luttmer R, Dijkstra MG, Snijders PJ, Jordanova ES, King AJ, Pronk DT, Foresta C, Garolla A, Hompes PG, Berkhof J, Bleeker MC, Doorbar J, Heideman DA, Meijer CJ. Presence of human papillomavirus in semen of healthy men is firmly associated with HPV infections of the penile epithelium. Fertil Steril. 2015 Oct;104(4):838-844.e8. doi: 10.1016/j.fertnstert.2015.06.028. Epub 2015 Jul 23. PubMed PMID: 26211884.

Luttmer R, Berkhof J, Dijkstra MG, van Kemenade FJ, Snijders PJ, Heideman DA, Meijer CJ. Comparing triage algorithms using HPV DNA genotyping, HPV E7 mRNA detection and cytology in high-risk HPV DNA-positive women. J Clin Virol. 2015 Jun;67:59-66. doi: 10.1016/j.jcv.2015.04.004. Epub 2015 Apr 7. PubMed PMID: 25959161.

Mensaert K, Van CW, Thas O, Schuuring E, Steenbergen RD, Wisman GB, De MT. Mining for viral fragments in methylation enriched sequencing data. Front Genet 2015;6:16.

Mooij SH, Van Santen DK, Geskus RB, Van Der Sande MA, Coutinho RA, Stolte IG, Snijders PJ, Meijer CJ, Speksnijder AG, De Vries HJ, King AJ, Van Eeden A, Van Der Loeff MF. The effect of HIV infection on anal and penile human papillomavirus incidence and clearance: a cohort study among MSM. AIDS. 2015 Oct 15. [Epub ahead of print]

Rodrigo JP, Hermsen MA, Fresno MF, Brakenhoff RH, García-Velasco F, Snijders PJ, Heideman DA, García-Pedrero JM. Prevalence of human papillomavirus in laryngeal and hypopharyngeal squamous cell carcinomas in northern Spain. Cancer Epidemiol. 2015 Feb;39(1):37-41. doi: 10.1016/j.canep.2014.11.003. Epub 2014 Nov 29. PubMed PMID: 25468644.

Schütze DM, Kooter JM, Wilting SM, Meijer CJ, Quint W, Snijders PJ, Steenbergen RD. Longitudinal assessment of DNA methylation changes during HPVE6E7-induced immortalization of primary keratinocytes. Epigenetics 2015;10:73-81.

Uijterwaal MH, Polman NJ, Van Kemenade FJ, Van Den Haselkamp S, Witte BI, Rijkaart D, Berkhof J, Snijders PJ, Meijer CJ. Five-Year Cervical (Pre)Cancer Risk of Women Screened by HPV and Cytology Testing. Cancer Prev Res (Phila). 2015 Jun;8(6):502-8. doi: 10.1158/1940-6207.CAPR-14-0409. Epub 2015 Mar 16.

Verdoodt F, Jentschke M, Hillemanns P, Racey CS, Snijders PJ, Arbyn M. Reaching women who do not participate in the regular cervical cancer screening programme by offering self-sampling kits: A systematic review and meta-analysis of randomised trials. Eur J Cancer. 2015 Nov;51(16):2375-85. doi: 10.1016/j.ejca.2015.07.006. Epub 2015 Aug 18. Review.

Verhoef VM, van Kemenade FJ, Rozendaal L, Heideman DA, Bosgraaf RP, Hesselink AT, Melchers WJ, Massuger LF, Bekkers RL, Steenbergen RD, Berkhof J, Snijders PJ, Meijer CJ. Follow-up of high-risk HPV positive women by combined cytology and bi-marker CADM1/MAL methylation analysis on cervical scrapes. Gynecol Oncol. 2015 Apr;137(1):55-9. doi: 10.1016/j.ygyno.2015.01.550. Epub 2015 Feb 8. PubMed PMID: 25667975.

Verlaat W, Snijders PJF, van Moorsel MIH, Bleeker MCG, Rozendaal L, Sie D, Ylstra B, Meijer CJLM, Steenbergen RDM, Heideman DAM.Somatic mutation in PIK3CA is a late event in cervical carcinogenesis. Journal of Pathology: Clinical Research 2015; 1 (4): 207–211. doi: 10.1002/cjp2.27.

Vink MA, Bogaards JA, Meijer CJ, Berkhof J. Primary human papillomavirus DNA screening for cervical cancer prevention: Can the screening interval be safely extended? Int J Cancer. 2015 Jul 15;137(2):420-7.

Welling CA, Mooij SH, van der Sande MA, van Rooijen MS, Vermeulen-Oost WF, King AJ, van Eeden A, Heideman DA, Stolte IG, Schim van der Loeff MF. Association of HIV Infection With Anal and Penile Low-Risk Human Papillomavirus Infections Among Men Who Have Sex With Men in Amsterdam: The HIV & HPV in MSM Study. Sex Transm Dis. 2015 Jun;42(6):297-304. doi: 10.1097/OLQ.0000000000000278. PubMed PMID: 25970305.

van Baars R, van der Marel J, Snijders PJ, Rodriquez-Manfredi A, Ter Harmsel B, van den Munckhof HA, Ordi J, Del Pino M, van de Sandt MM, Wentzensen N, Meijer CJ, Quint WG. CADM1 and MAL methylation status in cervical scrapes is representative of the most severe underlying lesion in women with multiple cervical biopsies. Int J Cancer. 2015 Jul 28. doi: 10.1002/ijc.29706. [Epub ahead of print].

van de Wiel MA, Lien TG, Verlaat W, van Wieringen WN, Wilting SM.Better prediction by use of co-data: adaptive group-regularized ridge regression.Stat Med. 2015 Sep 13. doi: 0.1002/sim.6732. [Epub ahead of print]

 

2014
Boers A, Bosgraaf RP, van Leeuwen RW, Schuuring E, Heideman DA, Massuger LF, Verhoef VM, Bulten J, Melchers WJ, van der Zee AG, Bekkers RL, Wisman GB. DNA methylation analysis in self-sampled brush material as a triage test in hrHPV-positive women. Br J Cancer. 2014 Sep 9;111(6):1095-101. doi: 10.1038/bjc.2014.392. Epub 2014 Jul 17. PubMed PMID: 25032730; PubMed Central PMCID: PMC4453842.

Bosgraaf RP, Ketelaars PJ, Verhoef VM, Massuger LF, Meijer CJ, Melchers WJ, Bekkers RL. Reasons for non-attendance to cervical screening and preferences for HPV self-sampling in Dutch women. Prev Med. 2014 Jul;64:108-13. doi:10.1016/j.ypmed.2014.04.011. Epub 2014 Apr 13. PubMed PMID: 24736093.

Chen AA, Heideman DA, Boon D, Gheit T, Snijders PJ, Tommasino M, Franceschi S,Clifford GM; IARC HPV Variant Study Group. Human papillomavirus 45 genetic variation and cervical cancer risk worldwide. J Virol. 2014 Apr;88(8):4514-21. doi: 10.1128/JVI.03534-13. Epub 2014 Feb 5. PubMed PMID: 24501412; PubMed Central PMCID: PMC3993765.

De Strooper LM, Hesselink AT, Berkhof J, Meijer CJ, Snijders PJ, Steenbergen RD, Heideman DA. Combined CADM1/MAL Methylation and Cytology Testing for Colposcopy Triage of High-Risk HPV-Positive Women. Cancer Epidemiol Biomarkers Prev. 2014 Sep;23(9):1933-7. doi: 10.1158/1055-9965.EPI-14-0347. Epub 2014 Jun 24. PubMed PMID: 24962840.

De Strooper LM, Meijer CJ, Berkhof J, Hesselink AT, Snijders PJ, Steenbergen RD, Heideman DA. Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2/3 lesions. Cancer Prev Res (Phila). 2014 Dec;7(12):1251-7. doi: 10.1158/1940-6207.CAPR-14-0237. Epub 2014 Oct 3. PubMed PMID: 25281488.

De Strooper LM, van Zummeren M, Steenbergen RD, Bleeker MC, Hesselink AT, Wisman GB, Snijders PJ, Heideman DA, Meijer CJ. CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer. J Clin Pathol. 2014 Dec;67(12):1067-71. doi:
10.1136/jclinpath-2014-202616. Epub 2014 Oct 3. PubMed PMID: 25281766.

Djajadiningrat RS, Horenblas S, Heideman DA, Sanders J, de Jong J, Jordanova ES. Classic and nonclassic HLA class I expression in penile cancer and relation to HPV status and clinical outcome. J Urol. 2015 Apr;193(4):1245-51. doi: 10.1016/j.juro.2014.11.057. Epub 2014 Nov 15. PubMed PMID: 25463996.

Dijkstra MG, van Niekerk D, Rijkaart DC, van Kemenade FJ, Heideman DA, Snijders PJ, Meijer CJ, Berkhof J. Primary hrHPV DNA testing in cervical cancer screening: how to manage screen-positive women? A POBASCAM trial substudy. Cancer Epidemiol Biomarkers Prev. 2014 Jan;23(1):55-63. doi: 10.1158/1055-9965.EPI-13-0173. Epub 2013 Jun 3. PubMed PMID: 23733907.

Dijkstra MG, Snijders PJ, Arbyn M, Rijkaart DC, Berkhof J, Meijer CJ. Cervical cancer screening: on the way to a shift from cytology to full molecular screening. Ann Oncol. 2014 May;25(5):927-35. doi: 10.1093/annonc/mdt538. Epub 2014 Jan 19. PubMed PMID: 24445150.

Foliaki S, Brewer N, Pearce N, Snijders PJ, Meijer CJ, Waqatakirewa L, Clifford GM, Franceschi S. Prevalence of HPV infection and other risk factors in a Fijian population. Infect Agent Cancer. 2014 Apr 28;9:14. doi:10.1186/1750-9378-9-14. eCollection 2014. PubMed PMID: 24891876; PubMed Central PMCID: PMC4040509.

Halec G, Alemany L, Lloveras B, Schmitt M, Alejo M, Bosch FX, Tous S, Klaustermeier JE, Guimerà N, Grabe N, Lahrmann B, Gissmann L, Quint W, Bosch FX, de Sanjose S, Pawlita M; on behalf of the Retrospective International Survey and HPV Time Trends Study Group; on behalf of the Retrospective International Survey and HPV Time Trends Study Group. Pathogenic role of the eight probably/possibly carcinogenic HPV types 26, 53, 66, 67, 68, 70, 73 and 82 in cervical cancer. J Pathol. 2014 Jul 16. doi: 10.1002/path.4405. [Epub ahead of print] PubMed PMID:
25043390.

Hesselink AT, Heideman DA, Steenbergen RD, Gök M, van Kemenade FJ, Wilting SM, Berkhof J, Meijer CJ, Snijders PJ. Methylation marker analysis of self-sampled cervico-vaginal lavage specimens to triage high-risk HPV-positive women for colposcopy. Int J Cancer. 2014 Aug 15;135(4):880-6. doi: 10.1002/ijc.28723. Epub 2014 Jan 28. PubMed PMID: 24474183.

Luyten A, Buttmann-Schweiger N, Luyten K, Mauritz C, Reinecke-Lüthge A, Pietralla M, Meijer CJ, Petry KU. Early detection of CIN3 and cervical cancer during long-term follow-up using HPV/Pap smear co-testing and risk-adapted follow-up in a locally organised screening programme. Int J Cancer. 2014 Sep 15;135(6):1408-16. doi: 10.1002/ijc.28783. Epub 2014 Feb 27. PubMed PMID:
24519782.

Meijer CJ, Snijders PJ. Cervical cancer in 2013: Screening comes of age and treatment progress continues. Nat Rev Clin Oncol. 2014 Feb;11(2):77-8. doi:10.1038/nrclinonc.2013.252. Epub 2014 Jan 21. Review. PubMed PMID: 24445518

Miok V, Wilting SM, van de Wiel MA, Jaspers A, van Noort PI, Brakenhoff RH, Snijders PJ, Steenbergen RD, van Wieringen WN. tigaR: integrative significance analysis of temporal differential gene expression induced by genomic abnormalities.BMC Bioinformatics. 2014 Oct 2;15(1):327. doi: 10.1186/1471-2105-15-327.

Mollers M, Vriend HJ, van der Sande MA, van Bergen JE, King AJ, Lenselink CH, Bekkers RL, Meijer CJ, de Melker HE, Bogaards JA. Population- and type-specific clustering of multiple HPV types across diverse risk populations in the Netherlands. Am J Epidemiol. 2014 May 15;179(10):1236-46. doi:
10.1093/aje/kwu038. Epub 2014 Apr 8. PubMed PMID: 24714726.

Mooij SH, Landén O, van der Klis FR, van der Sande MA, de Melker HE, Coutinho RA, van Eeden A, van Rooijen MS, Meijer CJ, Schim van der Loeff MF. No evidence for a protective effect of naturally induced HPV antibodies on subsequent anogenital HPV infection in HIV-negative and HIV-infected MSM. J Infect. 2014 Oct;69(4):375-86. doi: 10.1016/j.jinf.2014.06.003. Epub 2014 Jun 12. PubMed PMID:24931579.

Mooij SH, Boot HJ, Speksnijder AG, Meijer CJ, King AJ, Verhagen DW, de Vries HJ, Quint WG, Molijn A, de Koning MN, van der Sande MA, van der Loeff MF.Six-month incidence and persistence of oral HPV infection in HIV-negative and HIV-infected men who have sex with men. PLoS One. 2014 Jun 4;9(6):e98955. doi:10.1371/journal.pone.0098955. eCollection 2014. PubMed PMID: 24896848; PubMed Central PMCID: PMC4045821.

Pinheiro C, Garcia EA, Morais-Santos F, Scapulatempo C, Mafra A, Steenbergen RD, Boccardo E, Villa LL, Baltazar F, Longatto-Filho A. Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix.BMC Cancer. 2014 Oct 8;14(1):751. [Epub ahead of print]

Rietbergen MM, Snijders PJ, Beekzada D, Braakhuis BJ, Brink A, Heideman DA, Hesselink AT, Witte BI, Bloemena E, Baatenburg-De Jong RJ, Leemans CR, Brakenhoff RH. Molecular characterization of p16-immunopositive but HPV DNA-negative oropharyngeal carcinomas. Int J Cancer. 2014 May 15;134(10):2366-72. doi:10.1002/ijc.28580. Epub 2013 Nov 19. PubMed PMID: 24249631.

Rodrigo JP, Heideman DA, García-Pedrero JM, Fresno MF, Brakenhoff RH, Díaz Molina JP, Snijders PJ, Hermsen MA. Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990-2009). Int J Cancer. 2014 Jan 15;134(2):487-92. doi: 10.1002/ijc.28355. Epub 2013 Jul 27.PubMed PMID: 23824638.

Ronco G, Dillner J, Elfström KM, Tunesi S, Snijders PJ, Arbyn M, Kitchener H, Segnan N, Gilham C, Giorgi-Rossi P, Berkhof J, Peto J, Meijer CJ; International HPV screening working group. Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials. Lancet. 2014 Feb 8;383(9916):524-32. doi: 10.1016/S0140-6736(13)62218-7. Epub 2013 Nov 3. PubMed PMID: 24192252.

Ronco G, Meijer CJ, Segnan N, Kitchener H, Giorgi-Rossi P, Peto J, Dillner J. HPV-based screening for prevention of invasive cervical cancer - Authors' reply. Lancet. 2014 Apr 12;383(9925):1295. doi: 10.1016/S0140-6736(14)60645-0. PubMed PMID: 24725577

Rositch AF, Mao L, Hudgens MG, Moses S, Agot K, Backes DM, Nyagaya E, Snijders PJ, Meijer CJ, Bailey RC, Smith JS. Risk of HIV acquisition among circumcised and uncircumcised young men with penile human papillomavirus infection. AIDS. 2014 Mar 13;28(5):745-52. doi: 10.1097/QAD.0000000000000092. PubMed PMID: 24149088; PubMed Central PMCID: PMC4074250.

Schütze DM, Snijders PJF, Bosch L, Kramer D, Meijer CJLM, Steenbergen RDM -Differential In Vitro Immortalization Capacity of Eleven (Probably) High-risk Human Papillomavirus Types. J Virology 2014 Feb;88(3):1714-24. doi:10.1128/JVI.02859-13.

Senkomago V, Backes DM, Hudgens MG, Poole C, Agot K, Moses S, Snijders PJ, Meijer CJ, Hesselink AT, Schlecht NF, Bailey RC, Smith JS. Acquisition and Persistence of High Viral Load HPV16 and HPV18 Infections in Men Enrolled in a Circumcision Trial in Kisumu, Kenya. J Infect Dis. 2014 Sep 26. pii: jiu535.[Epub ahead of print] PubMed PMID: 25261492.

Snellenberg S, Cillessen SA, van Criekinge W, Bosch L, Meijer CJ, Snijders PJ,Steenbergen RD. Methylation-mediated repression of PRDM14 contributes to apoptosis evasion in HPV-positive cancers. Carcinogenesis. 2014 Sep 18. pii:bgu197. [Epub ahead of print] PubMed PMID: 25233927.

Steenbergen RD, Snijders PJ, Heideman DA, Meijer CJ. Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions.Nat Rev Cancer. 2014 Jun;14(6):395-405. doi: 10.1038/nrc3728. Review.

Thomas LK, Bermejo JL, Vinokurova S, Jensen K, Bierkens M, Steenbergen R, Bergmann M, von Knebel Doeberitz M, Reuschenbach M -Chromosomal gains and losses in human papillomavirus-associated neoplasia of the lower genital tract – A systematic review and meta-analysis. Eur J Cancer. 2014 Jan;50(1):85-98. doi: 10.1016/j.ejca.2013.08.022.

Tshomo U, Franceschi S, Dorji D, Baussano I, Tenet V, Snijders PJ, Meijer CJ,Bleeker MC, Gheit T, Tommasino M, Clifford GM. Human papillomavirus infection in Bhutan at the moment of implementation of a national HPV vaccination programme.BMC Infect Dis. 2014 Jul 22;14:408. doi: 10.1186/1471-2334-14-408. PubMed PMID:25047665.

Uijterwaal M, Kocken M, Berkhof J, Bekkers RL, H M Verheijen R, Helmerhorst TJ, Meijer CJ. Posttreatment assessment of women at risk of developing high-grade cervical disease: proposal for new guidelines based on data from the Netherlands.J Low Genit Tract Dis. 2014 Oct;18(4):338-43. doi: 10.1097/LGT.0000000000000012. PubMed PMID: 24769656.

Uijterwaal MH, Verhoef VM, Snijders PJ, Meijer CJ. Arguments in favor of HPV testing for cervical screening and post-treatment CIN2+ monitoring. Expert RevMol Diagn. 2014 Apr;14(3):245-8. doi: 10.1586/14737159.2014.893829. Epub 2014 Mar6. PubMed PMID: 24598044.

Uijterwaal MH, Witte BI, Van Kemenade FJ, Rijkaart D, Ridder R, Berkhof J,Balfoort-van der Meij GA, Bleeker MC, Snijders PJ, Meijer CJ. Triaging borderline/mild dyskaryotic Pap cytology with p16/Ki-67 dual-stained cytology testing: cross-sectional and longitudinal outcome study. Br J Cancer. 2014 Mar 18;110(6):1579-86. doi: 10.1038/bjc.2014.34. Epub 2014 Feb 11. PubMed PMID:
24518601; PubMed Central PMCID: PMC3960614.

van Aar F, Mooij SH, van der Sande MA, Meijer CJ, King AJ, Verhagen DW, Heijman T, Coutinho RA, Schim van der Loeff MF. Twelve-month incidence and clearance of oral HPV infection in HIV-negative and HIV-infected men who have sex with men: the H2M cohort study. BMC Infect Dis. 2014 Dec 31;14:668.

Veldhuijzen NJ, Berkhof J, Gillio-Tos A, De Marco L, Carozzi F, Del Mistro A, Snijders PJ, Meijer CJ, Ronco G. The age distribution of type-specific high-risk human papillomavirus incidence in two population-based screening trials. CancerEpidemiol Biomarkers Prev. 2014 Oct 9. pii: cebp.0628.2014. [Epub ahead of print]PubMed PMID: 25300476.

Verhoef VM, Bosgraaf RP, van Kemenade FJ, Rozendaal L, Heideman DA, Hesselink AT, Bekkers RL, Steenbergen RD, Massuger LF, Melchers WJ, Bulten J, Overbeek LI, Berkhof J, Snijders PJ, Meijer CJ. Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROHTECT-3): a randomised controlled non-inferiority trial. Lancet Oncol. 2014 Mar;15(3):315-22. doi: 10.1016/S1470-2045(14)70019-1. Epub 2014 Feb 13. PubMed PMID: 24529697.

Verhoef VM, Heideman DA, van Kemenade FJ, Rozendaal L, Bosgraaf RP, Hesselink AT, Bekkers RL, Massuger LF, Steenbergen RD, Snijders PJ, Berkhof J, Meijer CJ. Methylation marker analysis and HPV16/18 genotyping in high-risk HPV positive self-sampled specimens to identify women with high grade CIN or cervical cancer. Gynecol Oncol. 2014 Oct;135(1):58-63. doi: 10.1016/j.ygyno.2014.08.003. Epub 2014 Aug 8. PubMed PMID: 25111387.